5,6-Alkylenepyrimidine derivative

Details 5,6-Alkylenepyrimidine derivative 5,6-Alkylenepyrimidine derivative

1980-06-16

1982-10-05

Daus, Donald G.

Harness for working animal

544116, 544253, 424251, 4242484, C07D40304, C07D40514, C07D41304, A61K 31505

Patent

active

043529283

ABSTRACT:
There are provided a novel compound, i.e., a 2-piperazino-4-substituted-5,6-alkylenepyrimidine derivative represented by the formula: ##STR1## wherein Y, Z and n are defined in the specification and claims, and a pharmaceutically acceptable acid addition salt thereof.
The compounds of the present invention show, an anti-inflammatory effect, a blood sugar level lowering effect, a blood platelet aggregation suppressive effect, an anorexigenic action and a Serotonin effect.

REFERENCES:
patent: 3299068 (1967-01-01), Chinn
patent: 3635979 (1972-01-01), Hess
patent: 3757017 (1973-09-01), Mathieu
patent: 3925213 (1976-01-01), Hess
patent: 3980650 (1976-09-01), Nauta
McOmie, ed., "Protective Groups in Organic Chemistry," Plenum Press, London & New York (1973).

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