Formulation preparation device

Chemistry: analytical and immunological testing – Including sample preparation – Volumetric liquid transfer

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

422103, G01N 110

Patent

active

055830528

ABSTRACT:
A formulation preparation device is provided herein which contains a valve assembly, transfer spikes, syringe port and tube, these components being interconnected so as to provide for controlled fluid flow between the spikes and port, through the assembly, in specific directions only. The device has an enclosed, sterilizable, gripable housing and can be used to mix combine fluids in reproducible and predetermined proportions. Combination is accomplished aseptically, avoiding contact between the device's operator and the fluids and the substances combined. Biologically active compounds can be combined with one or more fluids, including such aqueous liposome suspensions, using the device. A formulation preparation kit containing, in addition to the device, the fluids and compounds to be formulated is thus also provided herein; methods of using the device to prepare such formulations are further provided herein.

REFERENCES:
patent: 2409343 (1946-10-01), Curtis
patent: 4098275 (1978-07-01), Consalvo
patent: 4244378 (1981-01-01), Brignola
patent: 4475914 (1984-10-01), Portnoff
patent: 4522803 (1985-06-01), Lenk et al.
patent: 4588578 (1986-05-01), Fountain et al.
patent: 4655763 (1987-04-01), Maclolm et al.
patent: 4721612 (1988-01-01), Janoff et al.
patent: 4729401 (1988-03-01), Raines
patent: 4787898 (1988-11-01), Raines
patent: 4823833 (1989-04-01), Hogan et al.
patent: 4915688 (1990-04-01), Bischoff et al.
patent: 4975282 (1990-12-01), Cullis et al.
patent: 5008050 (1991-04-01), Cullis et al.
patent: 5012845 (1991-05-01), Averette
patent: 5030453 (1991-07-01), Lenk et al.
patent: 5037390 (1991-08-01), Raines et al.
patent: 5059421 (1991-10-01), Loughrey et al.
patent: 5077056 (1991-12-01), Bally et al.
patent: 5100662 (1992-03-01), Bolcsak et al.
patent: 5169637 (1992-12-01), Lenk et al.
Bangham, et al., "Diffusion of Univalent Ions Across the Lamellae of Swollen Phospholipids", J. Mol. Boil. 13:228, 1965.
Cullis, et al., "Liposomes as Pharmaceuticals", in: Liposomes, From Biophysics to Therapeutics (M. Ostro, ed.,), Marcek Dekker, New York (1987), pp. 39-72.
Deamer, et al., "Liposome Preparation: Methods and Mechanisms" in: Liposomes (M. Ostro, ed.), Marcel Dekker, New York, (1983), pp. 27-51.
Gruner, "Materials Properties of Liposomal Bilayers", in:Liposomes, From Biophysics to Therapeutics, (M. Ostro, ed.) Marcel Dekker, New York 1987, pp. 1-38.
Papahadjopoulos, et al., "Phospholipid Model Membranes I. Structural Characteristics of Hydrated Liquid Crystals," BBA, 135:624, 1967.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Formulation preparation device does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Formulation preparation device, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Formulation preparation device will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-423716

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.