Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Reexamination Certificate
2009-08-24
2010-12-21
Duffy, Patricia A (Department: 1645)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
C530S387900, C435S975000
Reexamination Certificate
active
07855272
ABSTRACT:
An isolated extracellular matrix-binding protein, designated as SdrE and its corresponding amino acid and nucleic acid sequences and motifs are described. The proteins, peptides, fragments thereof or antigenic portions thereof are useful for the prevention, inhibition, treatment and diagnosis ofS. aureusinfection and as scientific research tools. Further, antibodies or antibody fragments to the proteins, peptides, fragments thereof or antigenic portions thereof are also useful for the prevention, inhibition, treatment and diagnosis ofS. aureusinfection. In particular, the proteins or antibodies thereof may be administered to wounds or used to coat biomaterials to act as blocking agents to prevent or inhibit the binding ofS. aureusto wounds or biomaterials.
REFERENCES:
patent: 94/13310 (1994-06-01), None
Yacoub et al (Eur. J. Bioche. 222:919-925, 1994).
Eidhin Deidre Ni
Foster Timothy J.
Hook Magnus A. O.
Josefsson Elisabet
Patti Joseph M.
Bioresearch Ireland
Duffy Patricia A
Schulman B. Aaron
Stites & Harbison PLLC
The Texas A&M University System
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