Cyclic amides

Details Cyclic amides Cyclic amides

1997-08-29

1999-03-02

Kight, John

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548450, 548451, A61K 3140, C07D20956

Patent

active

058772006

ABSTRACT:
Cyclic amides are inhibitors of tumor necrosis factor and can be used to combat cachexia, endotoxic shock, and retrovirus replication. A typical embodiment is 3-phenyl-3-(1-oxoisoindolin-2-yl)propionamide.

REFERENCES:
patent: 5276165 (1994-01-01), Weyer
patent: 5520844 (1996-05-01), Venturello
patent: 5654431 (1997-08-01), Meng
patent: 5728844 (1998-03-01), Muller

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