Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-06-05
2010-06-08
Aulakh, Charanjit S (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C546S048000
Reexamination Certificate
active
07732458
ABSTRACT:
A method for preparing dehydrocavidine, dehydroapocavidine and their respective composition is provided. The composition is first prepared by isolating and purifying the quaternary ammonium alkaloid components from the medicinal plant “Yan Huang Lian” (Corydalis saxicolaBunting) through the processes of solvent extraction, water-phase organic extraction, crystallization and recrystallization, and then drying to obtain said composition containing dehydrocavidine and dehydroapocavine. When necessary, the composition or their crude extracts can be separated by chromatography to obtain dehydrocavidine or dehydroapocavidine. Dehydrocavidine, dehydroapocavidine or their respective composition can be used in manufacturing medicines for treating viral hepatitis, hepatic injury, influenza, AIDS, tumors or arrhythmia.
REFERENCES:
patent: 200410099269.6 (2004-12-01), None
patent: WO 2006/069512 (2006-07-01), None
Bhakuni, D.S. et al.: The alkaloids of Corydalis Meifolia. J. of Natural Products, vol. 46, pp. 320-324, 1983.
Li Hui-Liang et al.: Bioavailability and pharmacokinetics of four active alkaloids of traditional chinese medicine Yanhuanglian in rats following intravenous and oral administration. J. of Pharmaceutical & Biomed. Anal. vol. 41, pp. 1342-1346, 2006.
Li Hanxiong
Li Huiliang
Liu Runhui
Su Juan
Xu Xike
Aulakh Charanjit S
Ho Ruay L.
IPFortune LLC
Li Hanxiong
LandOfFree
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