Intranasal vaccine for use against disease caused by...

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

Reexamination Certificate

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C424S184100, C424S185100, C424S234100, C530S300000, C530S326000

Reexamination Certificate

active

07666437

ABSTRACT:
The disclosure relates to an intranasal peptide vaccine for use against infection caused by enterotoxigenicEscherichia coli(ETEC), containing a common linear protein epitope known as CLE which is recognized by sera of patients infected with the bacteria and which is associated with a mucosal adjuvant comprising cholera toxin subunit B, known as CTB. The disclosure relates to a peptide containing twenty amino acids, which is located in the linear sequence of the CFA/I fimbria of enterotoxigenicEscherichia coli.

REFERENCES:
patent: 2003/0161889 (2003-08-01), Reid et al.
Lopez-Vidal et al. Continous and Common Epitopes Present in Fimbria. Gaceta Medica De Mexico. Nov.-Dec. 1997; 133 (6):511-525.

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