Method of use of gas mixtures to achieve nitrogen washout...

Details Method of use of gas mixtures to achieve nitrogen washout... Method of use of gas mixtures to achieve nitrogen washout...

2007-07-16

2010-02-16

Douglas, Steven O (Department: 3771)

Surgery

Respiratory method or device

C128S204180

Reexamination Certificate

active

07661424

ABSTRACT:
The disclosure details methods and gas mixtures which are useful for washing nitrogen out of the body and mitochondria following acute cerebrovascular accidents (strokes) or myocardial infarction (heart attacks) and allow the reuptake of oxygen into mitochondria of ischemic tissues following re-flow, thereby reducing the severity of reperfusion damage and cell death.

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Pan, Yi et al. Heliox and oxygen reduce infarct volume in a rat model of focal ischemia Exp. Neurol 205: 587-90 (2007).
Wade, CE et al. Absence of antiarrhythmic effects of helium in patients with spontaneous premature vantricular beats at rest Undersea Biomed Res. 6: 313-8 (1979).
Pifarre, MD. et al. Effect of oxygen and helium mixtures on ventricular fibrillation The Journal of Thoracic and Cardiovascular Surgery 60: 648-652 (1970).

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