Type III secretion pathway in Aeromonas salmonicida and...

Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Testing efficacy or toxicity of a compound or composition

Reexamination Certificate

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C424S009100, C424S184100, C424S185100, C424S190100, C424S234100, C424S246100, C530S300000, C530S350000, C536S023100, C536S023700

Reexamination Certificate

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07815896

ABSTRACT:
Disclosed is a newly identified and characterized type III secretion system inAeromonas salmonicida. The invention also encompasses the use of components of the novel secretion system in immunoprotection againstA. salmonicidainfection, as well as other diagnostic and therapeutic uses thereof.

REFERENCES:
Karlyshev, et al., Gene, 158:77-82 (1995).
Noonan, et al., Gene, 175:127-131 (1996).
Yahr, et al., Journal of Bacteriology, 179:22:7165-7168 (1997).
Yahr, et al., Database Accession No. AF010150, XP002216597.
Ellis, A.E., “Immunization with bacterial antigens: furunculosis”, Dev. Biol. Stand., vol. 90, pp. 107-116, 1997.
Thornton, J.C. et al., “Novel antigens expressed byAeromonas salmonicidagrown in vivo”, Infect. Immun., vol. 61, pp. 4582-4589, 1993.

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