Physiologically active substances, benastatins A and B, and prod

Details Physiologically active substances, benastatins A and B, and prod Physiologically active substances, benastatins A and B, and prod

1991-03-14

1992-05-26

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

C07C 5976, A01N 3710

Patent

active

051170523

ABSTRACT:
Benastatins A and B which are novel and physiologically active substances having the formula ##STR1## wherein R represents --CH.sub.2 --CH.sub.2 -- or --CH.dbd.CH--, exhibit a potent immunomodifier activity, a glutathione transferase inhibition activity and an anti-microorganism activity and are therefore extremely useful for various drugs.

REFERENCES:
Hollingworth, R. et al., Life Sci 13(3) 191-199, 1973.
Past, M. et al., Biochem. Biophys. Res Commun 52(4) 1123-8, 1973.
Ohkawa, H. et al., Pestic. Biochem. Physiol. 2(1) 95-112, 1972.
Ohkawa, H. et al. Biochem Pharmacol. 1973, 20(7) 1708-1711.

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