Direct mixing and injection for high throughput fluidic systems

Chemical apparatus and process disinfecting – deodorizing – preser – Control element responsive to a sensed operating condition

Reexamination Certificate

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C436S049000, C073S864010

Reexamination Certificate

active

07858040

ABSTRACT:
A system and method of mixing and injecting discrete sample mixtures into a flow cytometer or other sample analysis apparatus may generally comprise a sample injection guide coupling a liquid handling apparatus with a sample analysis apparatus and facilitating injection of discrete sample mixtures into a fluidic system of the apparatus.

REFERENCES:
patent: 4691580 (1987-09-01), Fosslien
patent: 5525302 (1996-06-01), Astle
patent: 5692220 (1997-11-01), Diamond et al.
patent: 5804436 (1998-09-01), Okun
patent: 5919646 (1999-07-01), Okun
patent: 6096509 (2000-08-01), Okun
patent: 6242209 (2001-06-01), Ransom
patent: 6280967 (2001-08-01), Ransom
patent: 6379917 (2002-04-01), Okun
patent: 6514722 (2003-02-01), Palsson
patent: 2001/0027269 (2001-10-01), Tanaka
patent: 2002/0170365 (2002-11-01), Sklar
patent: 2003/0013201 (2003-01-01), Sklar
patent: 2003/0040105 (2003-02-01), Sklar
patent: 2004/0025575 (2004-02-01), Petro et al.
patent: 0 645 631 (1995-03-01), None
patent: 1 229 448 (2003-01-01), None
patent: WO 01/59429 (2001-08-01), None
patent: WO 02/065121 (2002-08-01), None
Kuckuck, F. W., B. Edwards, and L. Sklar, “High throughput flow cytometry” Cytometry, 2001, 44(1): p. 83-90.
Pennings, A., P. Speth, H. Wessels and C. Haanen, “Improved flow cytometry of cellular DNA and RNA by on-line reagent addition” Cytometry, 1987, 8(3): p. 335-8.
Kelley, K.A., “Sample station modification providing on-line reagent addition and reduced sample transit time for flow cytometers” Cytometry, 1989, 10(6) 796-800, abstract only.
Kelley, K.A., “Very early detection of changes associated with cellular activation using a modified flow cytometer” Cytometry, 1991, 12(5): p. 464-8.
Lindberg, W., J. Ruzicka, and G. Christian, “Flow injection cytometry: a new approach for sample and solution handling in flow cytometry” Cytomertry, 1993, 14(2): p. 230-6.
Lindberg, W., L. Scampavia, J. Ruzicka and G. Christian, “Fast kinetic measurements and on-line dilution by flow injection cytometry” Cytometry, 1994, 16(4): p. 324-30.
Scampavia, L. D., G. Blankenstein, J. Ruzicka and G. Christian, “A coaxial jet mixer for rapid kinetic analysis in flow injection and flow injection cytometry” Anal. Chem., 1995, 67(17): p. 2743-9.
Blankenstein, G., L. Scampavia, J. Ruzicka and G. Christian, “Coaxial flow mixer for real-time monitoring of cellular responses in flow injection cytometry” Cytometry, 1996, 25(2): p. 200-4.
Dunne, J. F., “Time window analysis and sorting” Cytometry, 1991, 12(7): p. 597-601.
Steen, H. B., “A sample injection device for flow cytometers” Cytometry, 2002, 49(2): p. 70-2.
Abu-Absi, N. R., A. Zamamiri, J. Kacmar, S. Balogh and F. Sriene, “Automated flow cytometry for acquisition of time-dependent population data” Cytometry, 2003, 51A(2): 87-96.
Ramirez, S., C. Aiken, B. Andrzejewski, L. Sklar, and B. Edwards, “High-throughput flow cytometry: Validation in microvolume bioassays” Cytometry, 2003, 53A: p. 55-65.
JCSMR Flow Cytometry “An Introduction” http://jcsmr.anu.edu.au/facslab/intro.html.
Edwards, B. S., F. Kuckuck and L. A. Sklar, “Plug flow cytometry: An automated coupling device for rapid sequential flow cytometric sample analysis” Cytometry, 1999, 37 (2); p. 156-9.
Edwards, B., F. Kuckuck, E. Prossnitz, A. Okun, J. Ransom and L. Sklar, “Plug flow cytometry extends analytical capabilities in cell adhesion and receptor pharmacology” Cytometry, 2001 43(3), p. 211-6.
Edwards, B., F. Kuckuck, E. Prossnitz, J. Ransom and L. Sklar, “HTPS flow cytometry; a novel platform for automated high throughput drug discovery and characterization” J. Biomol. Screen., 2001, 6(2), p. 83-90.
Ransom, J.T., B. Edwards, F. Kuckuck, A. Okun, D. Mattox, E. Prossnitz and L. Sklar, “Flow cytometry systems for drug discovery and development” Optical Diagnostics for Living Cells, III Daniel L. Farkas, Robert C. Leif, editors, Proceedings of SPIE vol. 3921, 2000, p. 90-100.
Jackson, W. C., F. Kuckuck, B. Edwards, A. Mammoli, C. Gallegos, G. Lopez, T. Buranda and L. Sklar, “Mixing small volumes for continuous high-throughput flow cytomerty: Performance of a mixing Y and peristaltic sample delivery” Cytomerty, 2002, 47(3): p. 183-91.

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