Use of IL-18 inhibitors for treating head injuries

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C424S134100, C530S350000, C530S351000

Reexamination Certificate

active

07655616

ABSTRACT:
The invention relates to the use of inhibitors of IL-18 in the preparation of a medicament for treatment and/or prevention of central nervous system injury, in particular of traumatic head injury.

REFERENCES:
patent: 6566543 (2003-05-01), Mechoulam et al.
patent: 2002/0098185 (2002-07-01), Sims et al.
patent: WO 0185201 (2001-11-01), None
Fassbender, K., et al. (1999),Neurology, Lippincott, Williams&Wilkins, 53:1104-1106.
Altschul, et al.,J. Mol. Biol., 215:403-410 (1990).
Altschul, et al.,Nucleic Acids Research, 25:3389-3402 (1997).
Chen, et al.,J. of Neuro., 13:557-568 (1996).
Conti, et al.,Mol. Brain Res., 67:46-52 (1999).
Conti, et al.,J. of Bio. Chem., 272:2035-2037 (1997).
Culhane, et al.,Mol. Phsy., 3:362-366 (1998).
Devereux, et al.,Nuc. Acids Res., 12:387-395 (1984).
DiDonato, et al.,Nature, 388:548-554 (1997).
Elliott, et al.,Lancet, 344:1125-1127 (1994).
Jander, et al.,Jour. of Neuro., 91:93-99 (1998).
Jennett, et al.,Lancet, 480-484 (1975).
Izaki,Tohoku University, Faculty of Agriculture, Department of Agrochemistry, 6:729-742 (1978).
Kim, et al.,PNAS, 97:1190-1195 (2000).
Knight, et al.,Mol. Imm., 30:1443-1453 (1993).
Kossmann, et al.,J. of Cer. Blood Flow and Met., 17:280-289 (1997).
Maliszewski, et al.,Jour. of Imm., 144:3028-3033 (1990).
Morganti-Kossman, et al.,Mol. Psy., 2:133-136 (1997).
Miscallef, et al.,Eur. J. Imm., 26:1647-1651 (1996).
Nakamura, et al.,Inf. and Imm., 57:590-595 (1989).
Novick, et al.,Imm., 10:127-136 (1999).
Okamura, et al.,Inf and Imm., 63:3966-3972 (1995).
Parnett, et al.,Jour. of Bio. Chem., 271:3967-3970 (1996).
Pearson,Met. of Enzy., 183:63-98 (1990).
Pearson, et al.,Proc. Natl. Acad. Sci., 85:2444-2448 (1988).
Prinz, et al.,Jour. of Neuro., 72:2215-2218 (1999).
Rothe, et al.,Jour. of Clin. Inves., 99:469-474 (1997).
Scherbel, et al.,Proc. Natl. Acad. Sci., 96:8721-8726 (1999).
Shohami, et al.,Cyt. and Growth Fac. Rev., 10:119-130 (1999).
Shohami, et al.,Jour. of Cer. Blood Flow and Med., 17:1007-1019 (1997).
Stahel, et al.,Jour. of Cer. Blood Flow and Met., 20:369-380 (2000).
Teasdale, et al.,Lancet, 81-84 (1974).
Ushio, et al.,Jour. of Imm., 156:4274-4279 (1996).
Whalen, et al.,Crit. Care Med., 28:929-934 (2000).
Wheeler, et al.,Mol. Brain Res., 77:290-293 (2000).
Yoshimoto, et al.,Jour. of Imm., 161:3400-3407 (1998).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Use of IL-18 inhibitors for treating head injuries does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Use of IL-18 inhibitors for treating head injuries, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Use of IL-18 inhibitors for treating head injuries will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4202360

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.