Chemokine receptor binding heterocyclic compounds

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C514S307000, C514S311000, C514S313000, C546S134000, C546S135000, C546S159000, C546S164000, C546S171000

Reexamination Certificate

active

07807694

ABSTRACT:
Compounds which modulate chemokine receptor activities are disclosed. These compounds are preferably tertiary amines comprising tetrahydroquinoline and benzimidazole.

REFERENCES:
patent: 5021409 (1991-06-01), Murrer et al.
patent: 5583131 (1996-12-01), Bridger et al.
patent: 5698546 (1997-12-01), Bridger et al.
patent: 5817807 (1998-10-01), Bridger et al.
patent: 6001826 (1999-12-01), Murrer et al.
patent: 6365583 (2002-04-01), MacFarland et al.
patent: 11-269146 (1999-10-01), None
patent: WO-99/38514 (1999-08-01), None
patent: WO-00/42852 (2000-07-01), None
patent: WO-00/51607 (2000-09-01), None
patent: WO-00/56729 (2000-09-01), None
patent: WO-02/22599 (2002-03-01), None
patent: WO-02/22600 (2002-03-01), None
Este et al. “Activity of idifferent bicyclam . . . ” MOl. Pharm. 55, p. 67-73 (1999).
Abi-Younes et al., Clin. Res. (2000) 86:131-138.
Alkhatib et al., Science (1996) 272:1955-1958.
Arai et al., Eur. J. Haematol. (2000) 64:323-332.
Arenburg et al., J. Leukocyte Biol. (1997) 62:554-562.
Aiuti et al., J. Exp. Med. (1997) 185:111-120.
Baggiolini, Nature (1998) 392:565-568.
Bajetto et al., J. Neurochem. (1999) 73:2348-2357.
Berger et al., Annu. Rev. lmmunol. (1999) 17: 657-700.
Biard-Piechaczyk et al., Virology (2000) 268:329-344.
Blaak et al., Proc. Natl. Acad. Sci. (2000) 97:1269-1274.
Blanco et al., Antimicrobial Agents and Chemother (2000) 44:51-56.
Bleul et al., Nature (1996) 382:829-833.
Bleul et al., J. Exp. Med. (1998) 187:753-762.
Bradstock et al., Leukemia (2000) 14:882-888.
Bridger et al., “Bicyclam Derivatives as HIV Inhibitors” in Advances in Antiviral Drug Design vol. 3, pp. 161-229; Published by JAI press (1999); E. De Clercq (ed.).
Bridger et al., J. Med. Chem. (1999) 42:3971-3981.
Burger et al., Blood (1999) 94:3658-3667.
Buttini et al., Nature Med. (1998) 4:441-446.
Carroll et al., Science (1997) 276:273-276.
Cocchi et al., Science (1995) 270:1811-1815.
Connor and Ho, J. Virol. (1994) 68:4400-4408.
Deng et al., Nature (1996) 381:661-666.
Donzella et al., Nature Medicine (1998) 4:72-77.
Dragic et al., Nature (1996) 381:667-673.
Egberink et al., J. Virol. (1999) 73:6346-6352.
Eitner et al. Transplantation (1998) 66:1551-1557.
Fedyk et al., J. Leukocyte Biol. (1999) 66:667-673.
Feng et al., Science (1996) 272:872-877.
Gonzalo et al., J. Immunol. (2000) 165:499-508.
Gupta et al., J. Biol. Chem. (1998) 7:4282-4287.
Herbein et al., Nature (1998) 395:189-194.
Hesselgesser et al., “Chemokines and Chemokine receptors in the Brain” in Chemokines in Disease, published by Humana Press (1999) Herbert (ed.).
Hesselgesser et al. Curr. Biol. (1997) 7:112-121.
Hesselgesser et al., Curr. Biol. (1998) 8:595-598.
Ishii et al., J. Immunol. (1999) 163:3612-3620.
Lataillade et al., Blood (1999) 95:756-768.
Liu et al., Cell (1996) 86:367-377.
Locati et al., Annu. Rev. Med. (1999) 50:425-40.
Ma et al., Immunity (1999) 10:463-471.
Maekawa et al., Internal Medicine (2000) 39:90-100.
Michael et al., Nature Med. (1997) 3:338-340.
Michael et al., J. Virol. (1998) 72:6040-6047.
Miedema et al., Immune. Rev. (1994) 140:35.
Moore et al., J. Invest. Med. (1998) 46:113-120.
Moore et al., Trends Cardiovasc. Med. (1998) 8:51-58.
Murdoch et al., Blood (2000) 95:3032-3043.
Nagasawa et al., Nature (1996) 382:635-638.
Nagase et al., J. Immunol. (2000) 164:5935-5943.
Nanki et al., J. Immunol. (2000) 164:5010-5014.
Oberlin et al., Nature (1996) 382:833-835.
Obrien et al., Lancet (1997) 349:1219.
Ohagen et al., J. Virol. (1999) 73:897-906.
Peled et al., Science (1999) 283:845-848.
Peled et al., Blood (2000) 95:3289-3296.
Rana et al., J. Virol. (1997) 71:3219-3227.
Rizzuto et al., Science (1998) 280:1949-1953.
Salcedo et al., Am. J. Pathol. (1999) 154:1125-1135.
Samson et al., Nature (1996) 382:722-725.
Sanders et al., J. Neuroscience Res. (2000) 59:671-679.
Schols et al., Antiviral Research (1997) 35:147-156.
Schols et al., J. Exp. Med. (1997) 186:1383-1388.
Schuitemaker et al., J. Virol. (1992) 66:1354-1360.
Sehgal et al., J. Surg. Oncol. (1998) 69:99-104.
Simmons et al., J. Virol. (1998) 72:8453-8457.
Simmons et al., J. Virol. (1996) 70:8355-8360.
Tachibana et al., Nature (1998) 393:591-594.
Tersmette et al., J. Virol. (1998) 62:2026-2032.
Theodorou et al., Lancet (1997) 349:1219-1220.
Viardot et al., Ann. Hematol. (1998) 77:195-197.
Volin et al., Biochem. Biophys Res. Commun. (1998) 242:46-53.
Wyatt et al., Science (1998) 280:1884-1888.
Xia et al., J. Neurovirology (1999) 5:32-41.
Yssel et al., Clinical and Experimental Allergy (1998) 28:104-109.
Zhang et al., AIDS Res. Hum. Retroviruses (1997) 13:1357-1366.
Zhang et al., J. Virol. (1998) 72:9307-9312.
Zhang et al., J. Virol. (1999) 73:3443-3448.
Zheng et al., J. Virol. (1999) 73:8256-8267.
Zou et al., Nature, (1998) 393:591-594.
U.S. Appl. No. 60/172,153, filed Dec. 17, 1999.
U.S. Appl. No. 09/111,895, filed Jul. 8, 1998.
U.S. Appl. No. 09/535,314, filed Mar. 24, 2000.

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