Extract of Dioscorea opposita thunb showing neuronal...

Drug – bio-affecting and body treating compositions – Plant material or plant extract of undetermined constitution... – Containing or obtained from a root – bulb – tuber – corm – or...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C424S725000

Reexamination Certificate

active

07824718

ABSTRACT:
The present invention relates to a composition comprising an extract ofDioscorea oppositahaving neuron-protective activity for preventing and treating brain disease. The extracts fromDioscorea oppositashow potent neuronal cell protective activity by inhibiting neuronal cell death caused by neuro-toxicity of glutamate and H2O2therefore it can be used as the therapeutics or health food for treating and preventing brain diseases.

REFERENCES:
patent: 5589154 (1996-12-01), Anderson
patent: 1210722 (1999-03-01), None
Chung, H. Fractionation and Quantitative Analysis of Lipid Components in Korean Yam (Dioscorea) Tubers; Han'guk Nonghwa Hakhoechi (1994), 37(6), 509-15.
Medline Plus (online: URL< http://www.nlm.nih.gov/medlineplus/braindiseases.html > accessed Feb. 25, 2010, pp. 1-3).
Medline Plus online: URL< http://www.nlm.nih.gov/medlineplus/degenerativenervediseases.html > accessed Feb. 25, 2010, pp. 1-3).
Kermer et al. Neuronal Apoptosis in Neurodegenerative Diseases: From Basic Reasearch to Clinical Application; Neurodegenerative Diseases, 2004; 1, pp. 9-19.
Phillipson, J. New Drugs From Nature—It Could Be Yew; Phytotherapy Research 13 (1999) pp. 2-8.
Revilla et al. Comparison of Several Procedures Used for the Extraction of Anthocynains From Red Grapes; J. Agric. Food Chem. 1998, 46, pp. 4592-4597.
Plants for a Future database, online: URLhttp://www.pfaf.org/database/plants.php?Dioscorea+batatas, accessed Feb. 25, 2010, pp. 1-11.
Chung, H. Fractionation and Quantitative Analysis of Lipid Components in Korean Yam (Dioscorea) Tubers; Han'guk Nonghwa Hakhoechi (1994), 37(6), 509-15, full English translation.
Kirino T. Sano K., Acta Neuropathol., 62, pp. 201-208, 1984.
Kirino T. Brain Research, 239, pp. 57-69, 1982.
Kang T. C,, et al., J. Neurocytol., 30, pp. 945-955, 2001.
Won M. H., et al., Brain Research, 836, pp. 70-78, 1999.
Sun A. Y., Chen Y. M., J. Biomed. Sci., 5, pp. 401-414, 1998.
Zhao G. H et al., Acta Pharmaceutica Sinica, 38, pp. 37-41, 2003.
Kim et al., J. Neurosci. Res. 74, pp. 948-955, 2003.
Kim et al., Free Radic. Biol. Med., 32(7), pp. 596-604, 2002.
Kim et al., J. Neurosci. Res., 53, pp. 426-432, 1998.
Morris, J. Neurosci. Methods, 11, pp. 47-60, 1984.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Extract of Dioscorea opposita thunb showing neuronal... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Extract of Dioscorea opposita thunb showing neuronal..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Extract of Dioscorea opposita thunb showing neuronal... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4202057

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.