Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2003-10-16
2010-06-15
Wilson, James O (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S269000, C514S275000, C544S281000, C544S314000, C544S324000
Reexamination Certificate
active
07737153
ABSTRACT:
The invention relates to heteroaryloxy-substituted phenylaminopyrimidines, to methods for the production thereof, and to the use of the same for producing medicaments for the treatment and/or prophylaxis of diseases, especially cardiovascular diseases. The inventive compounds inhibit Rho-Kinase.
REFERENCES:
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Vippagunta et. al. Advanced Drug Delivery Reviews 48 (2001) 3-26.
Borisy, et. al., Proceedings of the National Academy of Sciences of the United States of America, 100(13) 7977-7982.
Fukata, Y., et al., “Rho- Rho-Kinase Pathway in Smooth Muscle Contraction and Cytoskeletal Reorganization of Non-muscle Cells”, Trends Pharm. Sci., 22(1): 32-39 (Jan. 2001).
Bennabi Samir
Ehmke Heimo
Feurer Achim
Figueroa Perez Santiago
Gnoth Jean Mark
Bayer Schering Pharma Aktiengesellschaft
DiCeglie, Jr. Nicholas J.
Edwards Angell Palmer & & Dodge LLP
Kramer Barry
Murray Jeffrey H
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