Low volume hybridization

Details Low volume hybridization Low volume hybridization

2005-12-28

2010-10-05

Forman, B J (Department: 1634)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S283100, C435S287200, C536S023100

Reexamination Certificate

active

07807354

ABSTRACT:
The present document relates to a system and method of commingling a low volume of a target solution with an array. For example, a quantity of the target solution and a quantity of an immiscible liquid may be introduced into a cavity having an array on an interior surface. The quantities of target solution and immiscible liquid do not fill the volume. Therefore, a gas is contained within the volume. The cavity is then agitated.

REFERENCES:
patent: 5059294 (1991-10-01), Lizardi
patent: 5549848 (1996-08-01), Zeheb et al.
patent: 6121055 (2000-09-01), Hargreaves
patent: 6171797 (2001-01-01), Perbost
patent: 6180351 (2001-01-01), Cattell
patent: 6232072 (2001-05-01), Fisher
patent: 6242266 (2001-06-01), Schleifer et al.
patent: 6258593 (2001-07-01), Schembri et al.
patent: 6323043 (2001-11-01), Caren et al.
patent: 6949624 (2005-09-01), Liu et al.
patent: 7060439 (2006-06-01), Gordon
patent: 2003/0087292 (2003-05-01), Chen et al.
patent: 2004/0241663 (2004-12-01), Peck et al.
patent: 2005/0176026 (2005-08-01), Franck et al.
patent: 2005/0271560 (2005-12-01), Rodgers et al.
Dressman et al “Transforming single DNA molecules into fluoescent magnetic particles for detection and enumeration of genetic variations” PNAS, 2003, 100(15): 8817-8822.
Kohne et al “Room temperature method for increasing the rate of DNA reassociation by many thousandfold: The phenol emulsion reassociation technique” Biochemistry, 1977 16(24): 5329-5341.
Yeh et al., Improving slide-based assays by stirring: Application of liquid-on-liquid mixing to immunofluorescence staining of polytene chromosomes, J. Biochem. Biophys. Methods, 2005, pp. 59-68, vol. 64.
Guttenberg et al., Planar chip device for PCR and hybridization with surface acoustic wave pump, Lab Chip, 2005, pp. 308-317, vol. 5.
European Patent Office Communication dated Apr. 27, 2007, enclosing the European Search Report and Annex dated Apr. 13, 2007, for EP Application No. 06256552, counterpart of U.S. Appl. No. 11/322,157.

Affiliated with

Also associated with

Rating

Low volume hybridization does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Low volume hybridization, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Low volume hybridization will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4194181