Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2007-08-14
2010-10-19
Fetterolf, Brandon J (Department: 1642)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C514S002600, C514S075000
Reexamination Certificate
active
07816097
ABSTRACT:
A nucleic acid sequence encoding Mammastatin, a specific mammary cell growth inhibitor. Mammastatin is encoded by a single nucleic acid sequence and has an approximate molecular weight of 44 kDa in its inactive, non-phosphorylated form. Normal mammary cells express functional phosphorylated forms having approximate molecular weights of 53 kDa and 49 kDa. Metastatic mammary cells either do not express Mammastatin at all, or do not express the 53 kDa or 49 kDa, phosphorylated forms. Mammary cancer cells are inhibited in their growth by the administration of phosphorylated mammastatin.
REFERENCES:
patent: 4379839 (1983-04-01), Spiegelman
patent: 4753894 (1988-06-01), Frankel
patent: 6451765 (2002-09-01), Ervin, Jr.
patent: 6492504 (2002-12-01), Ervin
patent: 6500937 (2002-12-01), Ervin, Jr.
patent: 6599495 (2003-07-01), Ervin
patent: 7256277 (2007-08-01), Ervin
patent: 7323173 (2008-01-01), Ervin, Jr.
patent: 7332287 (2008-02-01), Ervin
patent: 2008/0207506 (2008-08-01), Ervin
patent: 89/11491 (1989-11-01), None
patent: 89/11492 (1989-11-01), None
patent: WO 9811491 (1998-03-01), None
patent: 98/14577 (1998-04-01), None
patent: WO 9932625 (1999-07-01), None
patent: 00/78955 (2000-12-01), None
(Ervin, Paul R. Doctoral Dissertation University of Michigan, 1995).
Granziero et al. (Eur. J. Immunol. 1999, 29:1127-1138).
Byers, T. (CA Journal, vol. 49, No. 6, Nov./Dec. 1999).
Kohler, et al. (1975) Nature, 256:495 Continuous Cultures of Few Cells Cleaning Antibody a Predefined Specificity.
Kroczek, R.A. (1993) Journal of Chromatography, 618:133-145 Review: Southern and Northern analysis.
Kunkel, P., et al. “Expression and localization of scatter factor/hepatocyte growth factor in human astrocytomas,” (2001) Neuro-oncology 3(2):82-88.
Lasken, R.S., et al. (1985) Proceedings of the National Academy of Science USA 82(5):1301-1305, “A Fidelity Assay Using ‘dideoxy’ DNA sequencing: A measurement of sequence dependence and frequency of forming 5-bromouracil guanine base mispairs”.
Marx, J.L. (1986) Res. News, 30:1094 “The Yin and Yang of Cell Growth Control”.
McGrath, et al. (1984) In Vitro, 20:652 “Calcium Regulation of Normal Human Mammary Epithelial Cell Growth in Culture”.
McMahon, J.B., et al. (1984) J. Biol. Chem 259(3):1803 “Distribution and Subcellular Localization of Hepatic Proliferation Inhibitor in Rat Liver”.
MPSRCH Search Report (2006), us-10-326-242-3.n2p.rag, pp. 3-4.
Nakayama, K. et al. (1988) Bio/Technology, 6:693-697 “Construction of an ASD+ Expression-Cloning Vector: Stable Maintenance and High Level Expression of Cloned Genes in a Salmonella Vaccine Strain”.
Nguyen, B., et al. (1995) Critical Reviews and Oncology/Hematology, 20:223-236, “The Biology of Growth Regulation in Normal and Malignant Breast Epithelium: From Bench to Clinic”.
Nicola, N.A. et al. (1985) Cancer Survey 4(4):789 “Colony-Stimulation Factors and Myeloid Leukemia”.
Pigott et al. (1978) In Vitro, 14:360 “Inhibition of Growth of a Human Mammary Cell Line by Normal Human Growth”.
Sachs, L. (1986) Scientific American, pp. 40 “Growth Differentiation and the Reversal of Malignancy”.
Saxon, PJ et al. (1985) Mol. Cell. Biol. 5(1):140 “Selective Transfer of Individual Human Chromosomes to Recipient Cells”.
Short, J.M., (Aug. 11, 1988), Nucleic Acids Research, 16(15):7583-7601, “A ZAP: a bacteriophage expression vector with in vivo excision properties,”.
Soto, A.M. et al. (1984) Biochem. Biophys. Res. Comm., 122(3):1097 “Mechanism of Estrogen Action of Cellular Proliferation: Evidence for Indirect and Negative Control on Cloned Breast Tumor Cells”.
Soto, A.M., et al., (1986) Cancer Res. 46:2271 “Control of Cell Proliferation: Evidence for Negative Control on Estrogen-Sensitive T470 Human Breast Cancer Cells”.
Soule, et al. (1986) In Vitro Cellular & Developmental Biology, 22(1):6-12 “A Simplified Method for Passage and Long-Term Growth of Human Mammary Epithelial Cells”.
Spitler, Lynn E., “Cancer Vaccines: The Interferon Analogy,” (Cancer Biotherapy, 1995, 10:1-3).
Sporn, M.B., et al. (1987) J. Cell Biology, 105:1039 “Some Recent Advances in the Chemistry and Biology of Transforming Growth Factor-Beta”.
Strausberg et al., “National Cancer Institute, Cancer Genome Anatomy Project (CGAP)”, Sep. 28, 1998.
Stuckey, J.A., et al. (1994) Nature, 370:571-575 “Crystal structure of Yersinia protein tyrosine phophatase at 2.5 A and the complex with tungstate”.
Tian, J., et al. (2004) “The expression of native and cultured RPE grown on different matrices,” Physiol Genomics, 17:170-182.
Towbin, H., et al. (1989) Journal of Clinical Chemistry, Clinical Biochemistry, 27(8):495-501 “Immunoblotting in the Clinical Laboratory”.
Tucker, R.G., et al. (Nov. 1984) Science, 226:705 “Growth Inhibitor from BSC1 Cells Closely Related to Platelet Type-beta Transforming Growth Factor”.
Ullah et al. (1994) Biochemical and Biophysical Research Communications, 203(1): 182-189 “The Complete Primary Structure Elucidation ofAspergillus ficuum(NIGER), pH 6.0, Optimum Acid Phosphatase”.
Van Dyke, D.L., et al. (2003), “Monosomy 21 in hematologic diseases,” Cancer Genetics and Cytogenetics 241: 137-141.
William, E. Paul, 3rd ed. 1993, Fundamental Immunology, p. 242.
Zaslav, A., et al. “Significance of a Prenatally Diagnosed del(10)(q23)”, (2002) Amer J. Medical Genetics 107:174-176.
Perera, Frederica P., “Environment and Cancer: Who are Susceptible?”, Science, vol. 278, Nov. 7, 1997.
Lazar, et al., “Transforming Growth Factor . . . ” Molecular and Cellular Biology, Mar. 1988, pp. 1247-1252.
Blat, E., et al. (1986) Fed. Of Europe. Biochem. Soc., 203(2):175 “Inhibitor Diffusible Factor IDF45, A G1 Phase Inhibitor”.
Bohmer, et al. (1985) Biochem. Biophys. Acta, 846:145 “Specific Neutralizing Antiserum Against a Polypeptide Growth Inhibitor for Mammary Cells Purified from Bovine Mammary Glands”.
Bohmer, F.D. et al. (1984) Experimental Cell Research, 150:466 “Purification of a Growth Inhibitor for Ehrlich Ascites Mammary Carcioma Cell from Bovine Mammary Gland”.
Bohmer, F.D., et al. (1987) J. Biol. Chem. 26(31):15137 “Identification of a Polypeptide Growth Inhibitor from Bovine Mammary Gland”.
Boon (1992), “Toward a Genetic Analysis of Tumor Rejection Antigens,” Adv Can Res, 58:177-210).
Bowie, et al. “Deciphering the Message in Protein Sequences: Tolerance to Amino Acid Substitutions,” Science, 247:1306-1310, p. 1306.
Bronzert, D., et al. (1987) Cancer Research, 47:1234 “Estrogen Inhibitor of a M, 30,000 Glycoprotein Secreted by Human Breast Cancer Cells”.
Budzic, G.P., et al. (1985) Devel. Mech.: Normal and Abnormal, 207-223, Alan R. Liss, Inc. “A Possible Purification of Mullerian Inhibitory Substance and a Mocel for its Mechanism of Action”.
Burgess, A.W., et al. (1976) J. Cell Physiol., 90:471 “The Effect of Colony Stimulating Factor on a Synthesis of Ribonucleic Acid by Mouse Bone Marrow Cells in Vitro”.
Burgess, et al., J. of Cell Biol. 111:2129-2138 (1990).
Byers, T (CA Journal, vol. 49, No. 6, Nov./Dec. 1999).
Curti, Brendan D., (1993), “Physical barriers to drug delivery in tumors,” Crit. Rev. in Oncology/Hematology, 14:29-39.
Dalchau, et al. (1982) Monoclonal Antibodies in Clinical Medical, pp. 519-552 “The Purification of Antigens and Other Studies with Monoclonal Antibody Affinity Columns; the Complementary new Dimension of Monoclonal Anti-Bodies”.
Database Dissertation Abstracts Session No. AA19542835 (1995).
Dell Aquila, et al. (1984) Dissertation Abs. International, 75(6):1649B-1650B “Characterization and Purification of a Factor from Plasma Derived Human Serum which Inhibits the Growth of t
Casimir Jones SC
Fetterolf Brandon J
The Regents of the University of Michigan
LandOfFree
Nucleotide and protein sequence of Mammastatin and methods... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Nucleotide and protein sequence of Mammastatin and methods..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nucleotide and protein sequence of Mammastatin and methods... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4185884