Surface plasmon enhanced fluorescence sensor and...

Optics: measuring and testing – Of light reflection

Reexamination Certificate

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C356S448000

Reexamination Certificate

active

07738107

ABSTRACT:
A fluorescence sensor is constituted by: a light source, for emitting excitation light of a predetermined wavelength; a dielectric block, formed of a material that transmits the excitation light; a metal film, formed on a surface of the dielectric block; a non flexible film of a hydrophobic material, formed on the metal film at a film thickness within a range of 10 to 100 nm; a sample holding portion, for holding a sample such that the sample contacts the non flexible film; an incident optical system, for causing the excitation light to enter the interface between the dielectric block and the metal film through the dielectric block such that conditions for total internal reflection are satisfied; and fluorescence detecting means, for detecting fluorescence emitted by a substance within the sample, which is excited by evanescent waves that leak from the interface when the excitation light enters the interface.

REFERENCES:
patent: 5064619 (1991-11-01), Finlan
patent: 5341215 (1994-08-01), Seher
patent: 5629213 (1997-05-01), Kornguth et al.
patent: 6180288 (2001-01-01), Everhart et al.
patent: 6330062 (2001-12-01), Corn et al.
patent: 6784999 (2004-08-01), Tao et al.
patent: 6807323 (2004-10-01), Beom et al.
patent: 6956651 (2005-10-01), Lackritz et al.
patent: 6992770 (2006-01-01), Naya
patent: 7027163 (2006-04-01), Angeley
patent: 7193711 (2007-03-01), Rassman et al.
patent: 7273868 (2007-09-01), Yamada et al.
patent: 7297961 (2007-11-01), Kang et al.
patent: 2004/0023293 (2004-02-01), Kreimer et al.
patent: 2004/0091876 (2004-05-01), Yabuta et al.
patent: 2005/0158850 (2005-07-01), Kubo et al.
patent: 0353937 (1990-02-01), None
patent: 0517930 (1992-12-01), None
patent: 10078390 (1998-03-01), None
patent: 2003294610 (2003-10-01), None
patent: 0206838 (2002-01-01), None
Makio Tokunaga“Total Internal Reflection Fluorescence Micro-scopy that Enables Observation of Surfaces Only with High Image Quality”, “This Much Can Be Learned From Bio-Imaging”, pp. 104-113, Yodosha Press and a partial translation thereof.
Fang Yu et al.“Surface Plasmon Field-Enhanced Fluorescence Spectroscopy Studies of the Interaction between an Antibody and Its Surface-Coupled Antigen”, Analytical Chemistry, vol. 75, No. 11, pp. 2610-2617, Jun. 1, 2003.
Thorsten Lieberman and Wolfgang Knoll“Surface-Plasmon Field-Enhanced Fluorescence Spectroscopy”, Colloids and Surfaces vol. 171, pp. 115-130, 2000.

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