Myeloid progenitor inhibitory factor-1 (MPIF-1) polypeptides

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Lymphokines – e.g. – interferons – interlukins – etc.

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C530S350000, C530S326000, C530S327000, C530S328000, C530S329000

Reexamination Certificate

active

07851596

ABSTRACT:
There are disclosed therapeutic compositions and methods using isolated nucleic acid molecules encoding a human myeloid progenitor inhibitory factor-1 (MPIF-1) polypeptide (previously termed MIP-3 and chemokine β8 (CKβ8 or ckb-8)); a human monocyte-colony inhibitory factor (M-CIF) polypeptide (previously termed MIP1-γ and chemokine β1 (CKβ1 or ckb-1)), and a macrophage inhibitory protein-4 (MIP-4), as well as MPIF-1, M-CIF and/or MIP-4 polypeptides themselves, as are vectors, host cells and recombinant methods for producing the same.

REFERENCES:
patent: 4897348 (1990-01-01), Johnson et al.
patent: 5268463 (1993-12-01), Jefferson
patent: 5346686 (1994-09-01), Lyle et al.
patent: 5504003 (1996-04-01), Li et al.
patent: 5556767 (1996-09-01), Rosen et al.
patent: 5874211 (1999-02-01), Bandman et al.
patent: 5912327 (1999-06-01), Li et al.
patent: 6001606 (1999-12-01), Ruben et al.
patent: 6180773 (2001-01-01), Forssmann et al.
patent: 6403553 (2002-06-01), Opitz et al.
patent: 6451562 (2002-09-01), Ruben et al.
patent: 6488925 (2002-12-01), Ruben et al.
patent: 6495129 (2002-12-01), Li et al.
patent: 6623942 (2003-09-01), Ruben et al.
patent: 6811773 (2004-11-01), Antonaccio et al.
patent: 2003/0143191 (2003-07-01), Bell et al.
patent: 2003/0147846 (2003-08-01), Ruben et al.
patent: 2003/0158387 (2003-08-01), Forssman et al.
patent: 4344397 (1995-07-01), None
patent: 4427395 (1996-02-01), None
patent: 19512463 (1996-10-01), None
patent: 0 807 439 (1997-11-01), None
patent: WO-90/02762 (1990-03-01), None
patent: WO-91/04274 (1991-04-01), None
patent: WO-92/00326 (1992-01-01), None
patent: WO-92/00327 (1992-01-01), None
patent: WO-92/05198 (1992-04-01), None
patent: WO-92/13553 (1992-08-01), None
patent: WO-92/20372 (1992-11-01), None
patent: WO-93/09799 (1993-05-01), None
patent: WO-95/17092 (1995-06-01), None
patent: WO-95/18228 (1995-07-01), None
patent: WO-96/16979 (1996-06-01), None
patent: WO-96/22374 (1996-07-01), None
patent: WO-96/32481 (1996-10-01), None
patent: WO-96/34891 (1996-11-01), None
patent: WO-97/12041 (1997-04-01), None
patent: WO-97/15594 (1997-05-01), None
patent: WO-97/41230 (1997-11-01), None
patent: WO-98/14582 (1998-04-01), None
patent: WO-98/25966 (1998-06-01), None
patent: WO-01/31016 (2001-05-01), None
patent: WO-02/97038 (2002-12-01), None
Bischoff, S. C., et al., “Monocyte Chemotactic Protein 1 Is a Potent Activator of Human Basophils,” J. Exp. Med. 197:1271-1275 (1992).
Blum, S., et al., “Three Human Homologues of a Murine Gene Encoding an Inhibitor of Stem Cell Proliferation,” DNA and Cell Biology 9(8):589-602 (1990).
Chang, M., et al., “Cloning and Characterization of the Human Neutrophil-activating Peptide (ENA-78) Gene,”J. Biol. Chem. 269 (41):25277-25282 (1994).
Clements, J.M., et al., “Biological and Structural Properties of MIP-1.alpha. Expressed in Yeast,” Cytokine 4:76-82 (Jan. 1992).
Derynck, R., et al., “Recombinant Expression, Biochemical Characterization, and Biological Activities of the Human MGSA/gro Protein,” Biochem. 29:10225-10233 (Nov. 1990).
Glover, D.M., “The Principles of Cloning DNA,”in: Gene Cloning: The Mechanics of DNA Manipulation, Chapman and Hall, London, UK, pp. 1-20 (1984).
Graham, G. J. and Pragnell, I. B., “SCI/MIP-1.alpha.: A Potent Stem Cell Inhibitor with Potential Roles in Development,” Developmental Biol. 151:377-381 (1992).
Harlow, E. and Lane, D., from “Antibodies. A Laboratory Manual,”, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, p. 6 (1988).
Johnson, M. C., et al., “Cloning of Two Rabbit Gro Homologues and Their Expression in Alveolar Macrophage,” Gene 151:337-338 (1994).
Jose, P.J., et al., “Eotaxin: A Potent Eosinophil Chemoattractant Cytokine Detected in a Guinea Pig Model of Allergic Airways Inflammation,” J. Exp. Med. 179:881-887 (Mar. 1994).
Kuna, P. et al., “Monocyte Chemotactic and Activating Factor Is a Potent Histamine-releasing Factor for Human Basophils,” J. Exp. Med. 175:489-493 (Feb. 1992).
Kwon, B.S., and Weissman, S.M., “cDNA Sequences of two Inducible T-cell Genes,” Proc. Natl. Acad. Sci. USA 86:1963-1967 (Mar. 1989).
Lerner, R.A., “Tapping the Immunological Repertoire to Produce Antibodies of Predetermined Specificity,” Nature 229:592-596 (Oct. 1982).
Lukacs, N. W., et al., “The Role of Macrophage Inflammatory Protein 1.alpha. in Schistosoma mansoni Egg-induced Granulomatous Inflammation,” J. Exp. Med. 177:1551-1559 (1993).
Pardigol, A. et al., “HCC-2, a human chemokine: Gene structure, expression pattern, and biological activity,” Proc. Nat. Acad. Sci. USA 95, 6308-6313 (May 1998).
Matsushima, K., et al., “Purification and Characterization of a Novel Monocyte Chemotactic and Activating Factor Produced by a Human Myelomonocytic Cell Line,” J. Exp. Med. 169:1485-1490. (Apr. 1989).
Mikayama et al., “Molecular cloning and functional expression of a cDNA encoding glycosylation-inhibiting factor.” Proc Natl Acad Sci U S A. 90(21):10056-60 (Nov. 1, 1993).
Nakao, M., et al., “Structures of Human Genes Coding for Cytokine LD78 and Their Expression,” Molecular and Cellular Biology 10(10):3646-3658 (1990).
Obaru, K., et al., “A cDNA Clone Used to Study mRNA Inducible in Human Tonsillar Lymphocytes by a Tumor Promoter,” J. Biochem. 99(3):885-894 (1986).
Poltorak, A., et al., “Molecular Cloning of MIP-1.gamma., A New Member of the Chemokine Family, through Diffrential Screening Based on Extinction of Macrophage Specific Genes,” Clinical Research 42(2):306A XP000673113(Apr. 1994).
Poltorak, A. N., et al., “MIP-1.gamma.: Molecular Cloning, Expression, and Biological Activities of a novel CC Chemokine That Is Constitutively Secreted In Vivo,” J. Inflam. 45:207-219 (1995).
Power, C.A., et al., “Cloning of a Full-Length Cdna Encoding the Neutrophil-activating Peptide Ena-78 from Human Platlets,” Gene 151:333-334 (Jan. 1994).
Proost, P., et al., “Purification, Sequence Analysis, and Biological Characterization of a Second Bovine Monocyte Chemotactic Protein-1 (Bo MCP-1B),” Biochemistry33:13406-13412 (Nov. 1994).
Schall, T.J., “Biology of the RANTES/SIS Cytokine Family,” Cytokine 3:165-183 (May 1991).
Schulz-Knappe, P. et al., “HCC-1, a novel chemokine from human plasma,” J. Exp. Med. 183(1), 295-299 (1996).
Sudo, K., et al., “2058 Expressed Sequence Tags (ESTs) from a Human Fetal Lung cDNA Library,” Genomics 24:276-279 (Nov. 1994).
Voet et al. Biochemistry. John Wiley & Sons, Inc., pp. 126-128 and 228-234, 1990.
Weber, M., et al., “Deletion of the NH.sub.2 -Terminal Residue Converts Monocyte Chemotactic Protein 1 from an Activator of Basophil Mediator Release to an Eosinophil Chemoattractant,” J. Exp. Med. 183:681-685 (Feb. 1996).
Wolpe, S.D., and Cerami, A., “Macrophage Inflammatory Proteins 1 and 2: Members of a Novel Superfamily of Cytokines,” FASEB J. 3:2565-2573 (Dec. 1989).
Yoshida, T., et al., “Molecular Cloning of a Novel C or .gamma. Type Chemokine, SCM-1,” FEBS Letters 360:155-159 (Feb. 1995).
Zipfel, P.F., et al., “Mitogenic Activation of Human T Cells Induces two Closely Related Genes Which Share Structural Similarities with a New Family of Secreted Factors,” J. Immunol. 142:1582-1590 (Mar. 1989).
Search Report for EP 925671.3.
International Search Report for International Application No. PCT/US95/09058.
Derwent WPI, English language abstract for WO 95/18228.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Myeloid progenitor inhibitory factor-1 (MPIF-1) polypeptides does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Myeloid progenitor inhibitory factor-1 (MPIF-1) polypeptides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Myeloid progenitor inhibitory factor-1 (MPIF-1) polypeptides will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4177527

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.