Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2007-12-06
2010-02-16
Rao, Manjunath N. (Department: 1647)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C530S350000, C536S023500
Reexamination Certificate
active
07662576
ABSTRACT:
The Transient Receptor Potential Cation Channel, Subfamily A, Member 1 (TRPA1) protein has been identified as an ester cooler receptor and therefore is useful in screening assays for identifying ester coolers, in particular ester coolers with a relative cooling strength which exceeds (−)−menthol.
REFERENCES:
patent: 7018617 (2006-03-01), Tracey, Jr. et al.
patent: 2005/0202539 (2005-09-01), Chong et al.
patent: 2005/0265930 (2005-12-01), Erman et al.
patent: 2006/0142547 (2006-06-01), Bevan et al.
patent: WO 2005089206 (2005-09-01), None
NCBI Accession No. Y10601 [gi:4165268] with Revision History—Jun. 30, 1998-Apr. 18, 2005.
NCBI Accession No. NM—007332 [gi:116534989] with Revision History—Dec. 18, 1999-Sep. 25, 2007.
Bianchi et al., “Application of Large-Scale Transiently Transfected Cells to Functional Assays of Ion Channels:Different Targets and Assay Formats”, ASSAY and Drug Development Technologies 2007 5:417-424.
Hinman et al., “TRP channel activation by reversible covalent modification”, Proc Natl Acad Sci 2006 103 (51):19564-19568.
Jordt et al., “Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1”, Nature 2004: 417:260-265.
Macpherson et al., “Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines”, Nature 2007 445:541-545.
Sawada et al., “Cold sensitivity of recombinant TRPA1 channels”, Brain Research 2007 1160:39-46.
Smith et al., “Cold-sensitive, menthol-insensitive neurons in the murine sympathetic nervous system”, NeuroReport 2004 15(9):1399-1403.
Dewis Mark L.
Gravina Stephen Anthony
Kapur Vijyeta
Maxwell Carrie Ann
Montez Jason Michael
International Flavors & Fragrances Inc.
Licata & Tyrrell P.C.
Lockard Jon M
Rao Manjunath N.
LandOfFree
Method for identifying ester coolers does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for identifying ester coolers, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for identifying ester coolers will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4177371