Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Reexamination Certificate
2008-08-08
2010-10-26
Pak, Michael (Department: 1646)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Reexamination Certificate
active
07820791
ABSTRACT:
The invention relates to an isolated or recombinant Na+/H+exchanger comprising an isolated or recombinant Na+/H+exchanger, particularly to the PBO-4 Na+/H+exchanger. Also disclosed is an isolated or recombinant protein component of an H+-gated channel which can be affected by extracellular Ca2+concentration. In particular, the invention relates to PBO-5 and/or PBO-8 and/or a H+-gated channel composed of PBO-5 and PBO-8. The invention relates to compounds isolated from a vertebrate organism, wherein said compounds comprise at least a part of a H+-gated channel or Na+/H+exchanger. The invention also relates to a method for identifying a component of a H+-gated channel in a vertebrate organism.
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Beg Asim A.
Jorgensen Erik M.
Nix Paola
Ballard Spahr LLP
Pak Michael
University of Utah Research Foundation
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