Mouse developing visceral fat type obesity and diabetes

Multicellular living organisms and unmodified parts thereof and – Nonhuman animal – The nonhuman animal is a model for human disease

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C800S008000

Reexamination Certificate

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07847147

ABSTRACT:
An object of the present invention is to provide a mouse which has the characteristics of early developing visceral fat type obesity and also has concurrent diabetes and hyperlipemia and in which the trait is genetically established and recessively inherited. An ICR-derived mouse strain, Daruma, spontaneously developing obesity, exhibiting autosomal recessive inheritance for the trait of spontaneously developing obesity, and becoming obese only in the homozygous type is provided.

REFERENCES:
Allan et al. (2004) Obes. Res., vol. 12, 1397-1407.
Lewis and Warwick et al. (1953) J. Heredity, vol. 44, 233-238.
Sasaki et al. (2006) Japanese Society of Veterinary Science. The 142ndScientific Meetin go fthe Japanese Society of Veterinary Science, Aug. 31, 2006,I-26, p. 161, English translation abstract.
Eisen et al. (1988) J. Anim. Sci., vol. 66, 361-371.
Japanese Society of Veterinary Science, The 142nd Scientific Meeting of the Japanese Society of Veterinary Science, Yamaguchi University, Issued Aug. 31, 2006, I-26, p. 161 (with English translation).

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