Novobiocin analogues as anticancer agents

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

Reexamination Certificate

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C514S024000, C514S025000, C514S028000, C536S004100, C536S013000

Reexamination Certificate

active

07811998

ABSTRACT:
Novel analogues and derivatives of novobiocin are provided, including compounds having modifications to the amide side chain, coumarin ring, and sugar moieties. The compounds of the present invention are useful as heat shock protein 90 inhibitors, and may be used as anticancer and neuroprotective agents.

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