Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound
Reexamination Certificate
2007-09-27
2010-06-22
Vogel, Nancy (Department: 1636)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing oxygen-containing organic compound
C435S252300
Reexamination Certificate
active
07741084
ABSTRACT:
Production of ethanol using a strain of xylose-utilizingZymomonaswith a genetic modification of the glucose-fructose oxidoreductase gene was found to be improved due to greatly reduced production of xylitol, a detrimental by-product of xylose metabolism synthesized during fermentation.
REFERENCES:
patent: 5231020 (1993-07-01), Jorgensen et al.
patent: 5514583 (1996-05-01), Picataggio et al.
patent: 5712133 (1998-01-01), Picataggio et al.
patent: 5843760 (1998-12-01), Zhang et al.
patent: 6566107 (2003-05-01), Zhang
patent: 2002/0151034 (2002-10-01), Zhang
patent: 2003/0162271 (2003-08-01), Zhang et al.
patent: 1 600 850 (2005-03-01), None
patent: 1600850 (2005-03-01), None
patent: 95/28476 (1995-10-01), None
patent: 01/83784 (2001-11-01), None
patent: WO 2004/081185 (2004-09-01), None
U.S. Appl. No. 60/670,437, Apr. 12, 2005, James B. Dunson, Jr. et al.
U.S. Appl. No. 60/847,997, Sep. 28, 2005, Paul V. Vitanen et al.
Feldmann et al., Pentose Metabolism inZymomonas mobilisWild-Type and Recombinant Strains, Appl. Microbiol. Biotechnol., 1992, vol. 38:354-361.
Zhang et al., Metabolic Engineering of a Pentose Metabolism Pathway in EthanologenicZymomonas mobilis, Science, 1995, vol. 267:240-243.
Kim et al., Kinetic and Nuclear Magnetic Resonance Studies of Xylose Metabolism by RecombinantZymomonas mobilisZM4 (Pzb5), Applied and Environmental Microbiology, 2000, vol. 66:186-193.
Smith et al., D-Xylose (D-Glucose) Isomerase FromArthrobacterStrain N.R.R.L. B3728, Biochem. J., 1991, vol. 227:255-261.
Danielson, Limitations of Pentose Sugar Conversion in RecombinantZymomonas mobilisand Methods to Address These Limitations, University of Colorado Masters Thesis, 2001, p. 1-64.
Loos et al., Sorbitol Promotes Growth ofZymomonas mobilisin Environments With High Concentrations of Sugar: Evidence for a Physiological Function of Glucose-Fructose Oxidoreductase in Osmoprotection, J. Bacteriol., 1994, vol. 176:7688-7693.
Wiegert et al., Export of the Periplasmic NADP-Containing Glucose-Fructose Oxidoreductase ofZymomonas mobilis, Arch. Microbiol., 1996, vol. 166:32-41.
Kirk et al., Rapid Ethanol Production From Sucrose Without By-Product Formation, Biotechnol. Letters, 1993, vol. 15:985-990.
Sambrook et al., Molecular Cloning: A Laboratory Manual, 2NDEdition, 1989, Cold Spring Harbor (Book not Included).
Silhavy et al., Experiments With Gene Fusions, 1984, Cold Spring Harbor (Book not Included).
Ausubel et al., Current Protocls in Molecular Biology, 1987, Greene Publishing (Book not Included).
Mohagheghi et al., Cellular Biosensing System for Assessing Immunomodulating Effects on the Inducible Nitric Oxide Synthase (iNOS) Cascade, Biotechnol. Lett., 2003, vol. 25:321-325.
Zachariou et al., Glucose-Fructose Oxidoreductase, A New Enzyme Isolated FromZymomonas mobilisThat Is Responsible for Sorbitol Production, Journal of Bacteriology, 1986, vol. 167:863-869.
Lynd et al., Microbiol. Microbial Cellulose Utilization: Fundamentals and Biotechnology, Mol. Biol. Rev., 2002, vol. 66:506-577.
International Preliminary Report on Patentability in related PCT/US2007/020945 mailed Apr. 9, 2009.
Deshpande et al., Ethanol Production From Cellulose by Coupled Saccharification/Fermentation UsingSaccharomyces cerevisiaeand Cellulase Complex From Sclerotium Rolfsii UV-8 Mutant, Appl. Biochem. Biotechnol., 1992, vol. 36:227.
National Center for Biotechnology Information General Identifier No. 206201, Apr. 27, 1993, H. Inoue et al., Complete Amino Acid Sequence of Rat L-Type Pyruvate Kinase Deduced From the CDNA Sequence, Accession No. M17685.
National Center for Biotechnology Information General Identifier No. 58255, Nov. 14, 2006, R.E Rose, The Nucleotide Sequence of PACYC184, Accession No. X06403.
Kim et al., Nuclear Magnetic Resonance Studies of Acetic Acid Inhibition of RecZymomonasZM4 (pZB5), Applied Biochemistry and Biotechnology, 2000, vol. 84:357-370.
Sternberg et al., Bacteriophage P1 Site-Specific Recombination I. Recombination Between IoxP Sites, J. Mol. Biol., 1981, vol. 150:467-486.
Trinh et al., Site-Specific and Directional Gene Replacement Mediated by CRE Recombinase, Journal of Immunological Methods, 2000, vol. 244:185-193.
Sternberg et al., Bacteriophage P1 cre Gene and Its Regulatory Region Evidence for Multiple Promoters and for Regulation by DNA Methylation, J. Mol. Biol., 1986, vol. 187:197-212.
National Center for Biotechnology Information General Identifier No. 15135, Sep. 12, 1993, N. Sternberg et al., Bacteriophage P1 CRE Gene and Its Regulatory Region. Evidence for Multiple Promoters and for Regulation by DNA Methylation, Accession No. X03453.
Lawford et al., The Effect of Glucose on High-Level Xylose Fermentations by RecombinantZymomonasin Batch and Fed-Batch Fermentations, Appl. Biochem. & Biotech., 1999, vol. 77-79:235-249.
Joachimsthal et al., Characterization of a High-Productivity Recombinant Strain ofZymomonas mobilisfor Ethanol Production from Glucose/Xylose Mixtures, Appl. Biochem. & Biotechnol., 2000, vol. 84-86:343-356.
International Search Report for International Application No. PCT/US2007/020945 dated Jul. 4, 2008.
Lisa Kirk et al., Rapid Ethanol Production from Sucrose Without By-Product Formation, Biotechnology Letters, 1993, pp. 985-990, vol. 15, No. 9.
M. Zachariou et al., Glucose-Fructose Ozidoreductase, A New Enzyme Isolated FromZymomonas mobilisThat is Responsible for Sorbitol Production, Journal of Bacteriology, Sep. 1986, pp. 863-869, vol. 167, No. 3.
Caimi Perry G.
Chou Yat-Chen
Emptage Mark
McCutchen Carol M.
Viitanen Paul V.
Alliance for Sustainable Energy LLC
E. I. du Pont de Nemours and Company
Vogel Nancy
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