Methods of inhibiting the binding of P-selectin to PSGL-1...

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Monoclonal antibody or fragment thereof

Reexamination Certificate

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C424S130100, C424S133100, C424S141100, C424S143100, C424S152100, C424S173100, C530S387100, C530S387300, C530S388100, C530S388200, C530S388220, C530S388700

Reexamination Certificate

active

07824684

ABSTRACT:
This invention relates to anti-P-selectin antibodies and, in particular, to anti-P-selectin antibodies and variants thereof that contain an Fc part derived from human origin and do not bind complement factor C1q. These antibodies have new and inventive properties causing a benefit for a patient suffering from critical limb ischemia or peripheral arterial occlusive disease (CLI/PAOD).

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