Porphorymonas gingivalis polypeptides and nucleotides

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues

Reexamination Certificate

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C424S278100

Reexamination Certificate

active

07544777

ABSTRACT:
The present invention relates to isolatedPorphorymonas gingivalispolypeptides and nucleotides. The polypeptides include;an amino acid sequence selected from the group consisting of SEQ. ID. NO. 265 to SEQ. ID. NO. 528, SEQ. ID. NO. 531 and SEQ. ID. NO. 532; oran amino acid sequence at least 85%, preferably at least 95%, identical to an amino acid sequence selected from the group consisting of SEQ. ID. NO. 265 to SEQ. ID. NO. 528, SEQ. ID. NO. 531 and SEQ. ID. NO. 532; orat least 40 amino acids having a contiguous sequence of at least 40 amino acids identical to a contiguous amino acid sequence selected from the group consisting of SEQ. ID. NO. 265 to SEQ. ID. NO. 528, SEQ. ID. NO. 531 and SEQ. ID. NO. 532.

REFERENCES:
patent: 0 726 314 (1996-08-01), None
patent: WO 96/17936 (1996-06-01), None
Scolnick et al; Trends in Biotech; 18(1), pp. 34-39, 2000.
Database EMBL (online) Oct. 8, 1999; “Complete ORF22 sequence from Neisseria Meningitidis strain A”; retrieved from EBI Database Accession No. AAZ12027 & WO99/24578 (D6).
Chen, H.A., et al; “Immunodominant Antigens ofPorphyromonas gingivalisin Patient with Rapidly Progressive Periodontitis”;Oral Microbial Immunol; vol. 10; pp. 193-201 (1995).
Database Uniprot Online; “48 kDa Outer Membrane Protein”; Database Accession No. Q44130; XP-002302627.
Database Uniprot Online, “Na(+)-translocating NADH-quinone reductase subunit A (EC I.6.5.-) (Na(+)-translocating NQR su (Na(+)-NQR subunit A) (NQR complex subunit A) NQR-I subunit A)”; Database Accession No. P43955; XP-002302628.

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