Process for the introduction of fluoro substituents

Details Process for the introduction of fluoro substituents Process for the introduction of fluoro substituents

1995-09-06

1996-09-17

Lusignan, Michael

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

560131, 568 56, 570142, C07C 17013

Patent

active

055570089

ABSTRACT:
A one pot process for the perfluoroalkylation and/or perfluoroacyloxylation of organic substrates is provided. The process comprises contacting a substrate with a perfluoroalkanoic anhydride in the presence of an inorganic peroxygen compound at a temperature of greater than 10.degree. C. Substrates that can be perfluoroalkylated and/or perfluoroacyloxylated include alkylbenzenes, halogenated aromatic compounds, alkoxybenzenes, aryl benzenes, and aromatic and aliphatic disulphides. Preferably, the perfluoroalkanoic anhydride is trifluoroacetic anhydride and the inorganic peroxygen compound is sodium percarbonate.

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