Process for the preparation of hydrocortisone

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07J 2100

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055569625

ABSTRACT:
A compound of the formula ##STR1## wherein K is a protective group of the oxo of the formula ##STR2## wherein n is 2 or 3 and L is a 11.beta.-hydroxy, the dotted line in the 11-position is not a bond and X is chlorine, bromine or iodine which avoids an 11-hydroxylation step in the preparation of hydrocortisone.

REFERENCES:
patent: 4093720 (1978-06-01), Rousseau et al.
patent: 5182381 (1993-01-01), Philibert et al.

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