Method of enhancing cardiac tissue repair by administering a...

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Amino acid sequence disclosed in whole or in part; or...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C424S198100, C530S350000, C514S002600, C514S012200

Reexamination Certificate

active

07638128

ABSTRACT:
A purified paracrine factor of a mesenchymal stem cell, such as a Secreted frizzled related protein (Sfrp) is useful to reduce cell death an/or tissue injury associated with ischemic conditions.

REFERENCES:
patent: WO 03/062376 (2003-07-01), None
patent: WO 2004/044142 (2004-05-01), None
patent: WO 2004/087874 (2004-10-01), None
Skolnick et al. From genes to protein structure and function: novel applications of computational approaches in the genomic era. Trends in Biotech 18(1): 34-39, 2000.
Bork, A. Powers and pitfalls in sequence analysis: the 70% hurdle. Genome Res 10: 398-400, 2000.
Doerks et al. Protein annotation: detective work for function prediction. Trends in Genetics 14(6): 248-250, 1998.
Smith et al. The challenges of genome sequence annotation or “The devil is in the details”. Nature Biotech 15: 1222-1223, 1997.
Brenner, S.E. Errors in genome function. Trends in Genetics 15(4): 132-133, 1999.
Bork et al. Go hunting in sequence databases but watch out for the traps. Trends in Genetics. 12(10): 425-427, 1996.
Wells. J.A. Additivity of mutational effects in proteins. Biochemistry 29 (37): 8509-8517, 1990.
Ngo et al. Computational complexity, protein structure prediction, and the Levinthal paradox. The Protein Folding Problem and Tertiary Structure Prediction, pp. 492-495, 1994.
Barandon et al. Frizzled A, a novel angiogenic factor: promises for cardiac repair. Eur J Cardiothoracic Surg 25(1): 76-83, 2004.
Dufourq et al. FrzA, a secreted Frizzled related protein, induced angiogenic response. Circulation 106(24): 3097-3103, 2002.
Mirotsou et al. Secreted frizzled related protein 2 (Sfrp2) is the key Akt-mesenchymal stem cell-released paracrine factor mediating myocardial survival and repair. Proc Natl Acad Sci USA 104(5): 1643-1648, 2007.
Alvarez-Dolado et al.Nature, 425:968-973 (2003).
Barandon et al.Circulation, 108:2282-2289 (2003).
Beltrami et al.Cell, 114:763-776 (2003).
Bergmann et al.J. Mol. Cell. Cardiol., 37:681-690 (2004).
Caplice et al.Nat. Clin. Pract. Cardiovasc. Med., 1(2):90-95 (2004).
Dimmeler et al.J. Clin. Invest., 115(3):572-583 (2005).
Fazel et al.J. Clin. Invest., 116(7):1865-1877 (2006).
Gnecchi et al.Nat. Med., 11(4):367-368 (2005).
Guo et al.Circulation, Abstract only, 114(18):515, Supplement II (Oct. 31, 2006).
Jones et al.BioEssays, 24:811-820 (2002).
Kawano et al.J. Cell Sci., 116(13):2627-2634 (2003).
Kinnaird et al.Circ. Res., 95:354-363 (2004).
Lee et al.J. Biol. Chem., 279(15):14602-14609 (2004).
Li et al.Genome Biol., 2(8):0032.1-0032.11 (2001).
Logan et al.Annu. Rev. Cell Dev. Biol., 20 :781-810 (2004).
Mangi et al.Nat. Med., 9(9):1195-1201 (2003).
Manji et al.J. Clin. Psychiatry, 61(Suppl. 9):82-96 (2000).
Melo et al.Circulation, 109:2386-2393 (2004).
Mercer et al.EMBO J., 19(14):3597-3607 (2000).
Mirotsou et al.Circulation, Abstract only, 112(17):660, Supplement (Nov. 17, 2005).
Moon et al.Science, 296:1644-1646 (2002).
Nakamura et al.Proc. Natl. Acad. Sci. USA, 100(10):5834-5839 (2003).
Pandur et al.Nature, 418:636-641 (2002).
Schneider et al.Genes Dev., 15:304-315 (2001).
Schumann et al.Cardiovasc. Res., 45:720-728 (2000).
Uren et al.J. Biol. Chem., 275(6):4374-4382 (2000).
Van Gijn et al.Cardiovasc. Res., 55:16-24 (2002).
Wang et al.Cancer Res., 65(19):8604-8607 (2005).
Xu et al.Nat. Med., 3(9):997-1004 (1997).
GenBank Accession No. BC036503, Oct. 2003.
Han et al., “Secreted Frizzled-related Protein 1 (SFRP1) Protects Fibroblasts from Ceraminde-induced Apoptosis”,J. Biol. Chem., 279(4):2832-2840 (2004).
Database EBI, “Protein Factor Discovery Related Isolated Human Polypeptide”, Tang et al., XP-002494344, Abstract only, Dec. 30, 2004.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method of enhancing cardiac tissue repair by administering a... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of enhancing cardiac tissue repair by administering a..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of enhancing cardiac tissue repair by administering a... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4138386

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.