Aminophenoxyacetic acid derivatives and pharmaceutical...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C514S314000, C514S318000, C514S322000, C514S323000, C514S331000

Reexamination Certificate

active

07488738

ABSTRACT:
There is provided an aminophenoxyacetic acid derivative of the following formula (I):wherein, R1, R2, R3and R4are, independent from each other, alkoxy group, alkyl group or aryl group, etc.; E1and E2are oxygen atom, sulfur atom, etc.; n is 0 to 5; X and Y are alkylene group, cycloalkylen group, or alkenylen group; Q is phenyl group which may be substituted or benzoyl group, etc, or a pharmaceutically acceptable salt thereof.These compounds have neuroprotective effects by inducing calbindin D28Kd, one of Ca2+-binding proteins.

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