Myceliophthora thermophila laccase variants

Details Myceliophthora thermophila laccase variants Myceliophthora thermophila laccase variants

2000-12-07

2009-11-24

Pak, Yong D (Department: 1652)

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Oxidoreductase

C435S004000, C435S006120, C435S069100, C435S071100, C435S440000, C435S252300, C435S320100, C536S023200

Reexamination Certificate

active

07622287

ABSTRACT:
The present invention relates to a method of designing laccase mutants with increased oxidation potential and/or changed pH optimum and/or altered mediator pathway and/or altered O2/OH−-pathway, which method is based on the hitherto unknown three dimensional structure of laccases, wherein the parent laccase is aMyceliophthora thermophila, Polyporus pinsitus, orCoprinus cinereuslaccase.

REFERENCES:
patent: 5480801 (1996-01-01), Wahleithner et al.
patent: 5770419 (1998-06-01), Feng et al.
patent: 5925554 (1999-07-01), Pedersen et al.
patent: 5998353 (1999-12-01), Pedersen et al.
patent: 6008029 (1999-12-01), Yaver et al.
patent: 6060442 (2000-05-01), Svendsen
patent: 6140092 (2000-10-01), Pedersen et al.
patent: 6218170 (2001-04-01), Svendsen
patent: 6277611 (2001-08-01), Pedersen et al.
patent: WO 92/01046 (1992-01-01), None
patent: WO 95/07988 (1995-03-01), None
patent: WO 95/33836 (1995-12-01), None
patent: WO 95/33837 (1995-12-01), None
patent: WO 96/00290 (1996-01-01), None
patent: WO 96/06930 (1996-03-01), None
patent: WO 96/23874 (1996-08-01), None
patent: WO 97/09431 (1997-03-01), None
patent: WO-97/1999 (1997-06-01), None
Xu et al. Site-directed mutations in fungal laccase: effect on redox potential, activity, and pH profile. Biochem. J. (1998) 334:63-70.
Germann et al. Isolation and partial nucleotide sequence of the laccase gene fromNeurospora crassa: Amino acid sequence homology of the protein to human ceruloplasmin. Proc. Natl. Acad. Sci (1986) 83:8854-8858.
Cherry et al. Directed evolution of industrial enzymes: an update. Current Opinion in Biotechnol. (2003) 14:438-443.
Branden et al. Introduction to Protein Structure, Garland Publishing Inc., New York, p. 247, 1991.
Fernandez-Larrea et al. “Isolation and characterization of a laccase gene fromPodospor anserina.” Mol. Gen. Genet. 252:539-551(1996).
Xu et al., BBA, vol. 1292, pp. 303-311 (1996).
Messerschmidt et al., Chemical Abstracts, vol. 111, No. 3, p. 297 (1989).
Hanna et al., Biochem J., vol. 253, pp. 561-568 (1988).
Kojima et al., J. Biol. Chem., vol. 265, pp. 15224-15230 (1990).
Ducros et al., Acta Cryst., vol. D53, pp. 605-607 (1997).
Branden et al., Introduction to Protein Structure, pp. 269-271 (1991).
Soon-ja Kim et al., “Characteristics Of A Laccase Over-Secreting Mutant ofCoprinus Congregatus”, Fems Microbiology Letters, vol. 132, pp. 177-179 (1995).

Affiliated with

Also associated with

Rating

Myceliophthora thermophila laccase variants does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Myceliophthora thermophila laccase variants, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Myceliophthora thermophila laccase variants will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4133951