Levo and dextro dropropizine having antitussive activity

Details Levo and dextro dropropizine having antitussive activity Levo and dextro dropropizine having antitussive activity

1986-09-11

1987-10-13

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544392, A61K 31495, C07D24100

Patent

active

046999116

ABSTRACT:
The optical isomers of 3-(4-phenyl-1-piperazinyl)-1,2-propanediol, a process for the stereo-selective preparation and pharmaceutical composition containing the same as active principles are described.

REFERENCES:
patent: 3163649 (1964-12-01), Morren
patent: 4372958 (1983-02-01), Pestellini et al.
Morren, Chem. Abst. 56-2460d, eq. Belg. 601394.
Burger, Medicinal Chemistry Part II, 1980, Chapter Fifty-three, pp. 759-785.

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