Diacyl derivatives of glycerylphosphorylcholine, their preparati

Details Diacyl derivatives of glycerylphosphorylcholine, their preparati Diacyl derivatives of glycerylphosphorylcholine, their preparati

1985-12-02

1987-10-13

Berch, Mark L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Phosphorus containing other than solely as part of an...

546 2, 546 22, 558169, 556 26, C07F 958, A61K 31685

Patent

active

046999019

ABSTRACT:
The diacylesters, particularly bis(pyridyl-3-carboxilate) of glycerylphosphorylcholine, both optically active L(alpha) or racemic D, L(alpha) and their complexes having general formula: ##STR1## wherein: Y represents ##STR2## M represents Ca, Mg, Al, Zn X represents a halogen, particularly chlorine, n=2,3 ed m=0,1 are anti-dislipemic and cerebroactive agents.
Their preparation takes place through acylation with an anhydride of a complex of glycerylphosphorylcholine with calcium or zinc chloride.

REFERENCES:
Tanaka, Chem. Abs. 78, 97970n.

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