Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2007-03-05
2009-08-18
Whisenant, Ethan (Department: 1634)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S029000, C435S030000, C435S032000, C435S261000, C536S022100, C536S023100, C536S024300
Reexamination Certificate
active
07575868
ABSTRACT:
Methods are provided for accurately predicting efficacy of chemotherapeutic agents. Methods of the invention increase the positive predictive value of chemosensitivity assays by assessing both the ability of a chemotherapeutic to destroy cells and the genetic propensity of those cells for resistance. Results obtained using methods of the invention provide insight into the in vivo effectiveness of a therapeutic, and lead to more effective chemotherapeutic treatment.
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Kornblith Paul L.
McDonald Sean
Cooley Godward Kronish LLP
Precision Therapeutics, Inc.
Whisenant Ethan
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