Acellular immunogenic compositions and acellular vaccine...

Details Acellular immunogenic compositions and acellular vaccine... Acellular immunogenic compositions and acellular vaccine...

2005-09-15

2009-02-17

Graser, Jennifer E (Department: 1645)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

C424S234100, C424S236100, C424S235100, C424S193100, C424S197110, C424S200100, C530S350000, C435S242000, C435S252300, C435S252310

Reexamination Certificate

active

07491404

ABSTRACT:
The invention concerns an acellular immunogenic or vaccine composition for producing antibodies againstBacillus anthraciscomprising a protective antigen (PA) and killed and optionally purified spores, obtained from mutating strains ofBacillus anthracisand their uses.

REFERENCES:
patent: 0 739 981 (1996-10-01), None
XP-000922808, S. Welkos, et al., “Comparative safety and efficacy againstBacillus anthracisof protective antigen and live vaccines in mice”, Microbial Pathogenesis, 1988, vol. 5, No. 3, pp. 127-140.
XP-000215550, P. Turnbull, “Anthrax vaccines: past, present and future”, Guildford Surrey, GB, vol. 9, No. 8, Aug. 1991, pp. 533-539.
A. Stepanov, et al., “Development of novel vaccines against anthrax in man”, Journal of Biotechnology, vol. 44, No. 1, pp. 155-160, Jan. 26, 1996.
XP-000922839, V. Abalakin, et al., “Protective and other biological propeties ofBacillus anthracissoluble antigens”, vol. 35, No. 1, pp. 83-91, 1991.
XP-00214827, I. Kravets, et al., “Mixed anthrax vaccine having improved quality”, Res. Instit., Jul. 1998, Derwent abstract only.
XP-002141826, V. Abalakin, et al., Zhurnal Mikrobiologii, Epidemiologii, Immunologii, No. 5, 1990, pp. 72-75.
C. Pezard, et al., “Protective immunity induced byBacillus anthracistoxin-deficient strains”, Infection and Immunity, vol. 63, No. 4, Apr. 1995, pp. 1369-1372.
B. Ivins, et al., “Immunization studies with attenuated strains ofBacillus anthracis”, Infection and Immunity, vol. 52, No. 2, May 1986, pp. 454-458.
B. Ivins, et al., “Recent advances in the development of an improved human anthrax vaccine”, Eur. J. Epidemiol, vol. 4, No. 1, Mar. 1988, pp. 12-19.

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