Thiazole compounds useful as inhibitors of protein kinase

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Details

C514S252140, C514S275000, C544S060000, C544S330000, C544S331000, C544S332000

Reexamination Certificate

active

07488727

ABSTRACT:
The present invention provides a compound of formula I:or a pharmaceutically acceptable derivative thereof. These compounds are inhibitors of protein kinases, particularly inhibitors of GSK3, Aurora2, and Syk mammalian protein kinases. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of utilizing those compounds and compositions in the treatment of various protein kinase mediated disorders.

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Erich A Nigg (Nature Review/Molecular Cell Biology, vol. 2, pp. 21-32, Jan. 2001).

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