Arylpiperazinyl compounds

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S255030

Reexamination Certificate

active

07491727

ABSTRACT:
The invention relates to 5-HT receptor agonists or antagonists. Novel arylpiperazinyl sulfonamide compounds represented by Formula I, and synthesis and uses thereof for treating diseases including those mediated directly or indirectly by 5-HT receptors, are disclosed. Such conditions include central nervous system disorders such as generalized anxiety disorder, ADD/ADHD, neural injury, stroke, and migraine. Methods of preparation and novel intermediates and pharmaceutical salts thereof are also included.

REFERENCES:
patent: 2722529 (1955-11-01), Fleming et al.
patent: 4948892 (1990-08-01), Tanabe et al.
patent: 5137901 (1992-08-01), Junge et al.
patent: 5300523 (1994-04-01), Junge et al.
patent: 5478828 (1995-12-01), Mattson et al.
patent: 5506246 (1996-04-01), Junge et al.
patent: 5585392 (1996-12-01), Junge et al.
patent: 5602124 (1997-02-01), Tehim et al.
patent: 5789412 (1998-08-01), Halazy et al.
patent: 6391882 (2002-05-01), Moltzen et al.
patent: 6423717 (2002-07-01), Bromidge et al.
patent: 6476050 (2002-11-01), Aquila et al.
patent: 6599904 (2003-07-01), Bromidge et al.
patent: 6635661 (2003-10-01), Cuny et al.
patent: 6645980 (2003-11-01), Cuny et al.
patent: 7153858 (2006-12-01), Dhanoa et al.
patent: 2001/0056090 (2001-12-01), Aquila et al.
patent: 2002/0016337 (2002-02-01), Cuny et al.
patent: 2002/0035113 (2002-03-01), Moltzen et al.
patent: 2002/0065265 (2002-05-01), Wu et al.
patent: 2002/0123499 (2002-09-01), Persons et al.
patent: 2002/0177721 (2002-11-01), Aquila et al.
patent: 2003/0050309 (2003-03-01), Aquila et al.
patent: 2003/0069233 (2003-04-01), Bromidge et al.
patent: 2003/0069418 (2003-04-01), Aquila et al.
patent: 2003/0073681 (2003-04-01), Hauske et al.
patent: 2003/0092694 (2003-05-01), Nilsson et al.
patent: 2003/0114436 (2003-06-01), Aquila et al.
patent: 2005/0171347 (2005-08-01), Emelen et al.
patent: 2006/0205737 (2006-09-01), Becker et al.
patent: 089089 (1983-09-01), None
patent: 0434561 (1991-06-01), None
patent: 661266 (1995-07-01), None
patent: 0946539 (1999-10-01), None
patent: 59029665 (1984-02-01), None
patent: 9202764 (1997-05-01), None
patent: WO-95/04049 (1995-02-01), None
patent: WO-0056712 (2000-09-01), None
patent: WO-03009850 (2003-02-01), None
Jones et al. Pharmacology, Biochemistry and Behavior, vol. 71, p. 555-568 (2002).
Weisler, Expert Opin.Emerging Drugs, vol. 12, pp. 423-434 (2007).
Jankovic, Mount Sinai Journal of Medicine, vol. 73, p. 682-689 (2006).
Brown et al. Drug Discovery Today, vol. 12, pp. 757-766 (2007).
Uchida et al. Chemical Abstracts vol. 127, No. 220471 (1997) (Abstract for JP 09202764, Aug. 5, 1997).
Bojarski, et al., Bioorganic Med. Chem., 10:3817-3827 (2002).
Oh, et al., Curr. Med. Chem., 8:999-1034 (2001).
Rasmussen, et al., J. Pharmacol. Experimental Therapeutics, 294(2):688-700 (2000).
Lopez-Rodriguez et al. J. Med. Chem. vol. 44, pp. 198-207 (2001).
Becker et al. J. Med. Chem. vol. 49, pp. 3116-3135 (2006).
International Search Report for Application No. PCT/US04/02858 dated Sep. 2, 2004 (1 page).
Supplementary European Search Report for Application No. EP 04 70 74 09 dated Dec. 18, 2006 (3 pages).
Art cited by Examiner in First Notification of Office Action from The State Intellectual Property Office of the People's Republic of China for Application No. 2004800055827 dated Sep. 29, 2006 (7 pages).

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