Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Reexamination Certificate
2004-01-30
2009-12-15
Richter, Johann R (Department: 1616)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
C514S450000, C514S210010, C514S320000, C514S321000, C514S337000, C504S100000
Reexamination Certificate
active
07632820
ABSTRACT:
Disclosed are compounds of the formulain which n is 0 or 1; X—Y is —CH═CH— or —CH2—CH2—; Z is —C(═O)—, —C(═S)— or —SO2—; R1is C1-C12alkyl, C3-C8cycloalkyl or C2-C12alkenyl; and R2is R3-Z-, R3—O-Z-, R4or -Z-N(R6)(R7); Q is O or —N—R5; R3and R4are for example H, C1C12alkyl, C2-C12alkenyl, C2-C12alkynyl, C3-C12zcycloalkyl, C5-C12cycloalkenyl, aryl or heterocyclyl; R5is for example H, C1-C8alkyl, hydroxy-C1-C8alkyl, C3-C8cycloalkyl, C2-C8alkenyl, C2-C8alkynyl, phenyl or benzyl; R6and R7are for example, H, unsubstituted or mono- to pentasubstituted C1-C12alkyl, unsubstituted or mono- to pentasubstituted C2-C12alkenyl or, if appropriate, an E/Z isomer, E/Z isomer mixture and/or tautomer thereof, in each case in free form or in salt form, are useful as pesticides.
REFERENCES:
patent: 4203976 (1980-05-01), Fisher et al.
patent: 4206205 (1980-06-01), Mrozik et al.
patent: 4427663 (1984-01-01), Mrozik et al.
patent: 4622313 (1986-11-01), Wyvrath, Jr. et al.
patent: 4831016 (1989-05-01), Mrozik et al.
patent: 4895837 (1990-01-01), Mrozik et al.
patent: 5057499 (1991-10-01), Mrozik et al.
patent: 5169839 (1992-12-01), Linn et al.
patent: 5192546 (1993-03-01), Abercrombie et al.
patent: 5208222 (1993-05-01), Meinke et al.
patent: 5229415 (1993-07-01), Linn et al.
patent: 5346698 (1994-09-01), Abercrombie et al.
patent: 5436355 (1995-07-01), Demchak et al.
patent: 5723488 (1998-03-01), Walshe
patent: 5945445 (1999-08-01), Barringer et al.
patent: 5981500 (1999-11-01), Bishop et al.
patent: 6605595 (2003-08-01), Omura et al.
patent: 6875727 (2005-04-01), Hofer et al.
patent: 6933260 (2005-08-01), Cassayare
patent: 7250402 (2007-07-01), Omura et al.
patent: 7378399 (2008-05-01), Casssayre et al.
patent: 2006/0140997 (2006-06-01), Pitterna et al.
patent: 2006/0205595 (2006-09-01), Pitterna et al.
patent: 2008/0051353 (2008-02-01), Jung et al.
patent: 001688 (1979-05-01), None
patent: 0259688 (1988-03-01), None
patent: 0266131 (1988-05-01), None
patent: 0340849 (1989-11-01), None
patent: 0343708 (1989-11-01), None
patent: 0375393 (1990-06-01), None
patent: 0411897 (1991-06-01), None
patent: 0456509 (1991-11-01), None
patent: 0465121 (1992-01-01), None
patent: 0506331 (1992-09-01), None
patent: 0519731 (1992-12-01), None
patent: 1160252 (2001-12-01), None
patent: WO 93/15099 (1993-08-01), None
patent: WO 95/20877 (1995-08-01), None
patent: WO 96/22300 (1996-07-01), None
patent: WO 02/068441 (2002-09-01), None
patent: WO 02/068442 (2002-09-01), None
patent: WO 03/020738 (2003-03-01), None
patent: WO 03/053988 (2003-07-01), None
patent: WO 2004/067534 (2004-08-01), None
U.S. Appl. No. 10/568,715, filed Feb. 17, 2006, Kasaba et al.
U.S. Appl. No. 10/488,225, filed Feb. 26, 2004, Tobler, et al.
U.S. Appl. No. 10/544,274, filed Aug. 3, 2005, Cassayre et al.
U.S. Appl. No. 10/544,281, filed Aug. 3, 2005, Quaranta et al.
U.S. Appl. No. 10/560,390, filed Mar. 22, 2006, Pitterna et al.
U.S. Appl. No. 10/543,643, filed Apr. 5, 2006, Pitterna et al.
U.S. Appl. No. 10/513,247, filed Nov. 2, 2004, Tobler et al.
U.S. Appl. No. 10/498,858, filed Jun. 14, 2004, Cassayre et al.
U.S. Appl. No. 11/319,686, filed Dec. 28, 2005, Pitterna et al.
U.S. Appl. No. 11/319,687, filed Dec. 28, 2005, Pitterna et al.
U.S. Appl. No. 10/539,274, filed Mar. 9, 2006, Maienfisch et al.
Yoshua et al.: Simultanious Determination of Residues of Emanectin and Its Metabolites, and Mibimectin, Ivermectin, and Abamectin in Crops by Liquid Chromatography w Fluorescence Detection. Journal of AOAC International vol. 84, No. 3 (910-917).
Wrzesinski et al. Isolation and Identification of Residues of 4″-(epi-Methylamino)-4″-deoxyavermectin Bla Benzoate from the Surface of Cabbage, Journal of Agricultural and Food Chemistry, vol. 44, 1996, pp. 304-312.
Meinke et al., “Affinity Probes for the Avermectin Binding Proteins”, J Med Chem 1992, 35, 3879-3884.
Jones, T K et al.: “Synthesis and Biological Activity of 4a,4-Disubstituted Avermectins”; Journal of Agriculture and Food Chemistry., American Chemical Society, 42 1994, p. 1786-1790.
Meinke et al. “Synthesis of Avermectin B1-4′-4′a -oxide: A Precursor to Potent Antihelmintic agents”, Biorganic Medicinal Chemistry Letters, vol. 2. 1992 p. 537.
Mrozik, H et al. “Avermectin Acyl Derivatives with Anti helmintic activity” Journal of Medicinal Chemistry, vol. 25, 1982, pp. 658-663.
Shoop et al Efficacy in Sheep and Pharmacokinetics in Cattle That Led to the Selection of Epinomectin as a Topical Endetocide for Cattle, International Journal for Parasitology, 1996, 26 (11), 1227-35.
Cvetovich, et al., Syntheses of 4″-epi-Amino-4″-deoxyavermectins B1, J. Org. Chem. 1994, 7704-7708.
Mrozik, et al, Deoxy-4″-aminoavermectins with Potent Broad Spectrum Antiparasitic Activities, Bioorg. Med. Chem. Lett. 1995, 2435.
Fisher, M, Structure-Activity Relationships of the Avermectins and Milbemycins, ACS Symposium Series, 1997, 658, 220-238.
Cassayre Jérôme
Jung Pierre
Kessabi Fiona Murphy
Maienfisch Peter
Pitterna Thomas
Brown Courtney
Jarecki-Black Judy
Kawalski, Esq. Thomas
Merial Limited
Merial Limited
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