Preparation of .alpha.-cyanocinnamaldehydes

Details Preparation of .alpha.-cyanocinnamaldehydes Preparation of .alpha.-cyanocinnamaldehydes

1977-05-12

1979-10-23

Coughlan, Jr., Paul M.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260465E, 260465K, 260465G, 544325, C07C12152, C07C12000

Patent

active

041720903

ABSTRACT:
Benzaldehydes are reacted with cyanoacetaldehyde, for which reaction the cyanoacetaldehyde can be produced from isoxazole in a basic medium. The reaction gives .alpha.-cyanocinnamaldehydes, the hydrogenation of which gives the corresponding dihydrocinnamyl compounds, which can be converted to 2,4-diaminopyrimidines by reaction with guanidine, using various methods.

REFERENCES:
patent: 3833637 (1974-09-01), Cobb
patent: 3855265 (1974-12-01), Cresswell et al.

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