Isoindoline compounds and methods of their use

Details Isoindoline compounds and methods of their use Isoindoline compounds and methods of their use

2008-02-15

2009-08-04

Anderson, Rebecca L (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S417000, C514S416000

Reexamination Certificate

active

07569597

ABSTRACT:
Novel isoindoline compounds are disclosed. Methods of treating, preventing and/or managing cancer, diseases and disorders associated with, or characterized by, undesired angiogenesis, and diseases and disorders mediated by PDE 4, using the compounds are also disclosed.

REFERENCES:
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patent: WO 00/55134 (2000-09-01), None
patent: WO 01/46183 (2001-06-01), None
patent: WO 03/014315 (2003-02-01), None
Zips et al. in vivo 2005, 19, 1-8.
Byrn et al. Solid-State Chemistry of Drugs, 2d, Chapter 11 Hydrates and Solvates, 233-247.
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Huang et al. Current Opinions in Chemical Biology 2001, 5, 432-438.
El-Nagger et al.,Indian Journal of Chemistry, Section B: Organic, Incl. Medicinal, Publications & Information Directorate, 20B(6): 514-517 (1981).
Sun et al.Shengwu Huaxue Yu Shengwu Wuli Xuebao(1964). 4(5), 539-50—CAS English Abstract.

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