Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Primate cell – per se
Reexamination Certificate
2004-02-13
2009-06-02
Weber, John P (Department: 1657)
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
Primate cell, per se
Reexamination Certificate
active
07541182
ABSTRACT:
The present invention provides methods for identifying patients at risk of developing preeclampsia. In further embodiments, the present invention relates to methods for the diagnosis of patients with preeclampsia.
REFERENCES:
Neala et al. Meeting abstract. Am J Obstetrics and Gynecology 2001;185(6-s1) p. s83.
Khong, T.Y., et al., “Inadequate maternal vascular response to placentation in pregnancies complicated by preeclampsia and by small-for-gestational age infants,” Br J Obstet Gynaecol, 93: 1049-59 (1986).
Zhou, Y. et al., “Preeclampsia is associated with failure of human cytotrophoblasts to mimic a vascular adhesion phenotype. One cause of defective endovascular invasion in this syndrome?”, J Clin Invest, 99: 2152-64 (1997).
Fisher, S.J., “The placenta dilemma,” Semin Reprod Med, 18: 321-6 (2000).
DeWolf, F., et al., “Ultrastructure of the spiral arteries in the human placental bed at the end of normal pregnancy,” Am J Obstet Gynecol, 117: 833-48 (1973).
Buemi, M., et al., “Is apoptosis cause of preeclampsia?”, Eur Rev Med Pharmacol Sci, 2: 185-8 (1998).
Levy, R., et al., “To be, or not to be, that is the question. Apoptosis in human trophoblast” Placenta, 21: 1-13 (2000).
Mor, G., et al., “Role of the Fas/Fas ligand system in female reproductive organs: survival and apoptosis,” Biochem Pharmacol, 64: 1305 (2002).
Straszewski, S.L., et al., “Confers Human Trophoblast Cell Resistance to Fas-Mediated Apoptosis,” Molecular Human Reproduction (2004) in press.
Smith, S.C., et al., “Increased placental apoptosis in intrauterine growth restriction,” Am J Obstet Gynecol, 177: 1395-401 (1997).
Levy, R., et al., “Trophoblast apoptosis from pregnancies complicated by fetal growth restriction is associated with enhanced p53 expression,” Am J Obstet Gynecol, 186: 1056-61 (2002).
Smith, S.C., et al., “Placental apoptosis in normal human pregnancy,” Am J Obstet Gynecol, 177: 57-65 (1997).
Aschkenazi, S., et al., “Differential regulation and function of the fas/fas ligand system in human trophoblast cells,” Biol Reprod, 66: 1853-61 (2002).
Chua, S., et al., “Trophoblast deportation in pre-eclamptic pregnancy,” Br J Obstet Gynaecol, 98: 973-9 (1991).
Johansen, M., et al., “Trophoblast deportation in human pregnancy—its relevance for preeclampsia,” Placenta, 20: 531-9 (1999).
Sargent, I.L., et al., “Clinical experience: isolating trophoblasts from maternal blood,” Ann N Y Acad Sci., 731: 154-61 (1994).
Knight, M., et al., “Shedding of syncytiotrophoblast microvilli into the maternal circulation in pre-eclamptic pregnancies,” Br J Obstet Gynaecol, 105: 632-40 (1998).
Kertesz, Z., et al., “Purification and characterization of a complex from placental syncytiotrophoblast microvillous membranes which inhibits the proliferation of human umbilical vein endothelial cells,” Placenta, 20: 71-9 (1999).
Mor, G., et al., “Fas-Fas ligand system induced apoptosis in human placenta and gestational trophoblastic disease,” American Journal of Reproductive Immunology, 40: 89-95 (1998).
Athayde, N., et al., “Interleukin 16 in pregnancy, parturition, rupture of fetal membranes, and microbial invasion of the amniotic cavity,” Am J Obstet Gynecol, 182: 135-41 (2000).
Romero, R., et al., “Further observations on the fetal inflammatory response syndrome: a potential homeostatic role for the soluble receptors of tumor necrosis factor alpha,” Am J Obstet Gynecol, 183: 1070-7 (2000).
Rudin, C.M., et al., “Apoptosis and disease: regulation and clincal relevance of programmed cell death,” Annu Rev Med, 48: 267-81 (1997).
DiFederico, E., et al., “Preeclampsia is associated with widespread apoptosis of placental cytotrophoblasts within the uterine wall,” Am J Pathol, 155: 293-301 (1999).
DeWolf, F., et al., “The ultrastructure of acute atherosis in hypertensive pregnancy,” Am J Obstet Gynecol, 123, 164-74 (1975).
Roberts, JM, “Preeclampsia: What We Know and What We Do Not Know,” Semin Perinatol 24: 24-8 (2000).
The Magpie Trial Collaborative Group, “Do women with pre-eclampsia, and their babies, benefit from magnesium sulphate? The Magpie Trial: a randomized placebo-controlled trial,” Lancet 359: 1877-90 (2002).
Williams, J.W., “Premature separation of the Normally Implanted Placenta,” Surg Gynecol Obstet 21(5): 541-554 (1915).
Chesley, L.C., “The Control of Hypertension in Pregnancy,” Obstet Gynecol Annu 10: 69-106 (1981).
Tatum, H.J. and Mule, J.G., The hypertensive action of blood from patients with pre-eclampsia, Am J Obstet Gynecol 83: 1028-35 (1962).
Tatum, H.J., “The Obstetric Patient with Toxemia,” Clin Obstet Gynecol 13: 233-48 (1964).
Pirani, B.B. and MacGillivray, I., “The effect of plasma retransfusion on blood pressure in the puerperium,”, AM J Obstet Gynecol 121: 221-6 (1975).
Gant, N.F., et al., “The Nature of Pressor Responsiveness to Angiotensin II in Human Pregnancy,” Obstet Gynecol 43(6): 854 (1974).
Gant, N.F., et al., “A Study of Angiotensin II Pressor Response throughout Primigravid Pregnancy,” J Clin Invest 52: 2682-9 (1973).
Zuspan, F.P., “Catecholamines: Their Role in Pregnancy and the Development of Pregnancy-Induced Hypertension,” J Reprod Med 23(3): 143-50 (1979).
Zuspan, F.P., “Urinary amine alterations in drug-addiction pregnancy,” Am J Obstet Gynecol 126(7): 955-64 (1976).
Krege, J.H. and Katz, V.L., “A Proposed Relationship Between Vasopressinase Altered Vasopressin and Preeclampsia,” Med Hypotheses 31: 283-7 (1990).
McKinney, E.T., et al., “Plasma, urinary, and salivary 8-epi-prostaglandin f2αlevels in normotensive and preeclamptic pregnancies,” Am J Obstet Gynecol 183(4): 874-7 (2000).
Clark, B.A., et al., “Plasma endothelin levels in preeclampsia: Elevation and correlation with uric acid levels and renal impairment,” Am J Obstet Gynecol 166(3): 962-8 (1992).
Pedersen, E.B., et al., “Renin, Angiotensin II, Aldosterone, Catecholamines, Prostaglandins and Vasopressin. The Importance of Pressor and Depressor Factors for Hypertension in Pregnancy,” Scand J Clin Lab Invest Suppl 169: 48-56 (1984).
Aalkjaer, C., et al., “Morphology and Angiotensin II Responsiveness of Isolated Resistance Vessels from Patients with Pre-eclampsia,” Scand J Clin Lab Invest Suppl 169: 57-60 (1984).
Neale, D., et al., “Maternal serum of women with pre-eclampsia reduces trophablast cell viability: evidence for an increased sensitivity to Fas-mediated apoptosis,” J Matern Fetal Neonatal Med 13: 39-44 (2003).
Polliotti, et al. “Second-Trimester Maternal Serum Placental Growth Factor and Vascular Endothelial Growth Factor for Predicting Severe, Early-Onset Preeclampsia”,Obstetrics&Gynecology, 101: 1266-1274, (2003).
Mor Gil G.
Neale Donna
Romero Roberto
Shen Bin
The United States of America as represented by the Department of
Weber John P
Wolf Greenfield & Sacks P.C.
Yale University
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