IBC-1 (invasive breast cancer-1), a putative oncogene...

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

Reexamination Certificate

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C530S300000, C530S380000, C530S385000, C530S386000, C530S387100, C530S387300, C530S387700, C530S387900, C530S388100, C530S388150, C530S388200, C436S063000, C436S064000, C436S174000, C435S004000, C435S006120, C435S007100, C435S007210, C435S007230, C424S130100, C424S138100, C424S139100, C424S141100, C424S142100

Reexamination Certificate

active

07608696

ABSTRACT:
This invention encompasses antibodies specific for IBC-1 (Invasive Breast Cancer-1), methods for diagnosis and prognosis of metastatic breast cancer and degenerative neural conditions, methods of identifying and manufacturing therapeutic compounds, and methods of treating patients with invasive and metastatic breast cancer or degenerative neural conditions.

REFERENCES:
patent: 5834192 (1998-11-01), Akerblom et al.
patent: 6262024 (2001-07-01), Cunningham et al.
patent: 2003/0224465 (2003-12-01), Nevalainen et al.
patent: WO/98/11136 (1998-03-01), None
Amino acid sequence alignmnent between Applicants' SEQ ID No. 4 (comprising SEQ ID No. 5, 6, 12 and 13) and seqeunce 2 of U.S. Patent No. 5,834,192 (issued Nov. 10, 1998).
Amino acid sequence alignmnent between Applicants' SEQ ID No. 4 (comprising SEQ ID No. 5 and sections of 6 and 12) and 13) and seqeunce 10 of U.S. Patent No. 6,262,024 (issued Jul. 17, 2001 and filed Sep. 18, 1997).
Editors: Cruse and Lewis. Illustrated Dictionary of Immunology. p. 241. CRC Press, Inc. 1995.
International Search Report from PCT/US02/34499 filed Oct. 28, 2002.

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