Modified human interferon-β polypeptides

Drug – bio-affecting and body treating compositions – Lymphokine – Interferon

Reexamination Certificate

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C435S069510, C435S442000, C530S351000

Reexamination Certificate

active

07632492

ABSTRACT:
The invention provides compositions and methods of identifying, modifying and producing modified target molecules, including therapeutic molecules by modification with non-natural amino acids. Certain aspects of the invention include methods of adding a chemical moiety to a target molecule, and the compositions resulting therefrom. Certain aspects of the invention also relate to kits for identifying, modifying and producing modified target molecules described herein.

REFERENCES:
patent: 4609546 (1986-09-01), Hiratani
patent: 4717569 (1988-01-01), Harrison et al.
patent: 4766106 (1988-08-01), Katre et al.
patent: 4849227 (1989-07-01), Cho
patent: 4894226 (1990-01-01), Aldwin et al.
patent: 4902502 (1990-02-01), Nitecki et al.
patent: 5122614 (1992-06-01), Zalipsky
patent: 5281698 (1994-01-01), Nitecki
patent: 5340589 (1994-08-01), Stetsko et al.
patent: 5382657 (1995-01-01), Karasiewicz et al.
patent: 5428128 (1995-06-01), Mensi-Fattohi et al.
patent: 5573783 (1996-11-01), Desieno et al.
patent: 5621039 (1997-04-01), Hallahan et al.
patent: 5622986 (1997-04-01), Greenwald et al.
patent: 5643575 (1997-07-01), Martinez et al.
patent: 5728560 (1998-03-01), Shorr et al.
patent: 5730990 (1998-03-01), Greenwald et al.
patent: 5738846 (1998-04-01), Greenwald et al.
patent: 5811076 (1998-09-01), Brasch et al.
patent: 5824701 (1998-10-01), Greenwald et al.
patent: 5840900 (1998-11-01), Greenwald et al.
patent: 5846917 (1998-12-01), Oumar-Mahamat et al.
patent: 5858660 (1999-01-01), Eaton et al.
patent: 5880131 (1999-03-01), Greenwald et al.
patent: 5900402 (1999-05-01), Shorr
patent: 5902588 (1999-05-01), Greenwald et al.
patent: 5919455 (1999-07-01), Greenwald et al.
patent: 5951974 (1999-09-01), Gilbert et al.
patent: 5965119 (1999-10-01), Greenwald et al.
patent: 5965566 (1999-10-01), Greenwald et al.
patent: 5969040 (1999-10-01), Hallahan et al.
patent: 5981709 (1999-11-01), Greenwald et al.
patent: 6004573 (1999-12-01), Rathi et al.
patent: 6011042 (2000-01-01), Greenwald et al.
patent: 6042822 (2000-03-01), Gilbert et al.
patent: 6127355 (2000-10-01), Greenwald et al.
patent: 6132713 (2000-10-01), Fiipula et al.
patent: 6177087 (2001-01-01), Greenwald et al.
patent: 6180095 (2001-01-01), Greenwald et al.
patent: 6188965 (2001-02-01), Mayo et al.
patent: 6248363 (2001-06-01), Patel et al.
patent: 6269312 (2001-07-01), Mayo et al.
patent: 6586207 (2003-07-01), Tirrell et al.
patent: 6638500 (2003-10-01), El-Tayar et al.
patent: 6708120 (2004-03-01), Mayo et al.
patent: 6737236 (2004-05-01), Pieken et al.
patent: 6792356 (2004-09-01), Mayo et al.
patent: 6801861 (2004-10-01), Mayo et al.
patent: 6804611 (2004-10-01), Mayo et al.
patent: 6951939 (2005-10-01), Jones
patent: 7026440 (2006-04-01), Bentley et al.
patent: 7045337 (2006-05-01), Schultz et al.
patent: 7083970 (2006-08-01), Schultz et al.
patent: 7139665 (2006-11-01), Datta et al.
patent: 7198915 (2007-04-01), Tirrell et al.
patent: 7354761 (2008-04-01), Schultz et al.
patent: 7368275 (2008-05-01), Schultz et al.
patent: 7375234 (2008-05-01), Sharpless et al.
patent: 7449443 (2008-11-01), Tirrell et al.
patent: 7462463 (2008-12-01), Tirrell
patent: 2002/0042097 (2002-04-01), Tirrell et al.
patent: 2002/0052443 (2002-05-01), Greenwald et al.
patent: 2002/0061307 (2002-05-01), Whitlow et al.
patent: 2002/0098192 (2002-07-01), Whitlow et al.
patent: 2003/0175241 (2003-09-01), Pedersen et al.
patent: 2004/0062746 (2004-04-01), Martinez et al.
patent: 2004/0062748 (2004-04-01), Martinez et al.
patent: 2004/0105839 (2004-06-01), Park
patent: 2004/0265952 (2004-12-01), Deiters et al.
patent: 2005/0032081 (2005-02-01), Ju et al.
patent: 2005/0054053 (2005-03-01), Aguinaldo et al.
patent: 2005/0220762 (2005-10-01), Cho et al.
patent: 2005/0250183 (2005-11-01), Schultz et al.
patent: 2005/0260711 (2005-11-01), Datta et al.
patent: 2005/0287639 (2005-12-01), Kwon et al.
patent: 2006/0246509 (2006-11-01), Deiters et al.
patent: 2007/0123693 (2007-05-01), Wilson
patent: 2007/0172459 (2007-07-01), Gantier et al.
patent: 2008/0003202 (2008-01-01), Guyon et al.
patent: 2008/0026422 (2008-01-01), Tirrell et al.
patent: 2008/0044854 (2008-02-01), Wang et al.
patent: 2008/0097083 (2008-04-01), Cho et al.
patent: 2008/0108791 (2008-05-01), Cho et al.
patent: 2008/0108792 (2008-05-01), Hays et al.
patent: 2008/0114155 (2008-05-01), Cho et al.
patent: 2008/0119640 (2008-05-01), Hays et al.
patent: 2008/0132681 (2008-06-01), Hays et al.
patent: 2008/0146781 (2008-06-01), Cho et al.
patent: 2008/0160609 (2008-07-01), Tirrell et al.
patent: 2008/0161539 (2008-07-01), Cho et al.
patent: 2008/0207877 (2008-08-01), Cho et al.
patent: WO 95/13090 (1995-05-01), None
patent: WO 96/21469 (1996-07-01), None
patent: WO 97/14740 (1997-04-01), None
patent: WO 99/27897 (1999-06-01), None
patent: WO 02/072019 (2002-09-01), None
patent: WO 02/085923 (2002-10-01), None
patent: WO 02/086075 (2002-10-01), None
patent: WO 2004/022593 (2004-03-01), None
patent: WO 2004/031352 (2004-04-01), None
patent: WO 2004/060299 (2004-07-01), None
patent: WO 2004/060300 (2004-07-01), None
patent: WO 2005/003157 (2005-01-01), None
patent: WO 2005/003294 (2005-01-01), None
patent: WO 2005/016371 (2005-02-01), None
patent: WO 2005/035727 (2005-04-01), None
patent: WO 2005/058346 (2005-06-01), None
patent: WO 2005/074524 (2005-08-01), None
patent: WO 2005/074650 (2005-08-01), None
patent: WO 2005/084303 (2005-09-01), None
patent: WO 2005/099769 (2005-10-01), None
patent: WO 2006/122972 (2006-11-01), None
patent: 2006/133088 (2006-12-01), None
patent: WO 2006/133089 (2006-12-01), None
patent: WO 2007/070672 (2007-06-01), None
patent: WO 2007/130453 (2007-11-01), None
Bork et al., Go hunting in sequence databases but watch out for the traps, 1996, Trends in Genetics, vol. 12, pp. 425-427.
Bork, Powers and Pitfalls in Sequence Analysis: the 70% hurdle, 2000, Genome Research, vol. 10, pp. 398-400.
Brenner, Errors in genome annotation, 1999, Trends in Genetics, vol. 15, pp. 132-132.
Doerks et al., Protein annotation: detective work for function prediction, 1998, Trends in Genetics, vol. 14, pp. 248-250.
Skolnick et al., From genes to protein structure and function: novel applications of computational approaches in the genomic era, 2000, Trends in Biotech, vol. 18, Issue 1, pp. 34-39.
Smith et al., The challenge of genome sequence annotation or “the devil is in the details”, 1997, Nature Biotechnology, vol. 15, pp. 1222-1223.
Blaskovich, M.A. et al., “Polymer-Supported Acetylide Addition to Hexa-2,4-dienal,”Synthesis 7:965-966, Jul. 1998.
Bowie, J.U. et al., “Deciphering the Message in Protein Sequences: Tolerance to Amino Acid Substitutions,”Science 247:1306-1310, Mar. 16, 1990.
Datta, D. et al., “A Designed Phenylalanyl-tRNA Synthetase Variant Allows Efficient in Vivo Incorporation of Aryl Ketone Functionality into Proteins,”Journal of the American Chemical Society 124(20):5652-5653, 2002.
Furter, R., “Expansion of the genetic code: Site-directedp-fluoro-phenylalanine incorporation inEscherichia coli,” Protein Science 7:419-426, 1998.
Geigert, J. et al., “The Long-Term Stability of Recombinant (Serine-17) Human Interferon-β,”Journal of Interferon Research 8:539-547, 1988.
Hirel, P.H. et al., “Extent of N-terminal methionine excision fromEscherichia coliproteins is governed by the side-chain length of the penultimate amino acid,”Proc. Natl. Acad. Sci. USA 86:8247-8251, Nov. 1989.
International Search Report for PCT/US2007/010631, Jan. 28, 2008.
Invitation to Pay Additional Fees (Partial International Search Report) for PCT/US2008/073763, Feb. 13, 2009.
Kiick, K. et al., “Incorporation of azides into recombinant proteins for chemoselective modification by the Staudinger ligation,”Proc. Natl. Acad. Sci. USA 99(1):19-24, Jan. 8, 2002.
Kwon, I.et al., “Breaking the Degeneracy of the Genetic Code,”Journal of the American Chemical Society 125:7512-7513, 2003.
Link, A.J. et al., “Cell Surface Labeling ofEscherichia colivia Copper(I)-Catalyzed [3+2] Cycloaddit

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