Liquid purification or separation – Processes – Chromatography
Reexamination Certificate
2005-03-17
2009-06-30
Therkorn, Ernest G (Department: 1797)
Liquid purification or separation
Processes
Chromatography
C210S635000, C210S198200
Reexamination Certificate
active
07553421
ABSTRACT:
Method for sizing the cells of a centrifugal liquid-liquid chromatography “column” (CPC column) consisting of stacked discs on which the cells connected in cascade (in series) by small channels are engraved. Rotation of the stack creates a high centrifugal acceleration field which makes it possible to keep a liquid phase referred to as stationary phase motionless, whereas a mobile phase circulates along the CPC column. The cells are three-dimensional, with two dimensions (L, l) of the cells oriented in a plane substantially normal to the axis of rotation (Ω) of the disc and a third dimension (e) oriented in a direction substantially parallel to the axis of rotation, and selected so as to be at least equal to one of the other two dimensions (L, l), thus providing higher efficiency. When the scale of the devices has to be changed, the size of the cells is modified ensuring that, in any case, this third dimension (e) is favored so as to be as great as possible.Applications: design of analytic or preparative chromatography devices.
REFERENCES:
patent: 4877523 (1989-10-01), Nunogaki
patent: 6537452 (2003-03-01), de La Poype et al.
patent: 2004/0173534 (2004-09-01), Margraff et al.
Google Translation of Apr. 11, 2008 of the first three full paragraphs of p. 5 of GEPEA Resultants 2001 Internet Article, Online Mar. 2, 2003, pp. 1-7.
Muratama et al.: A new centrifugal counter-current chromatograph and its application Journal of Chromatography, vol.: 239, Apr. 30, 1982 pp. 643-649.
Marchal et al.: “Influence of flow patterns on chromatographic efficiency in centrifugal partition chromatography” Journal or Chromatography A, vol. 869, Feb. 11, 2000, pp. 339-352.
Anonymous: GEPEA Resultats 2001 Internet Article, Online! Mar. 2, 2003, pp. 1-7.
Durand Daniel
Foucault Alain
Legrand Jack
Marchal Luc
Antonelli, Terry Stout & Kraus, LLP.
Institut Francais du Pe'trole
Therkorn Ernest G
Universite de Nantes
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