Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2003-01-24
2009-06-09
Hui, San-ming (Department: 1617)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C546S111000
Reexamination Certificate
active
07544696
ABSTRACT:
Hexahydroindenopyridine compounds are provided which act as spermicides and/or fungicides, spermicidal and/or fungicidal compositions containing the same, and methods for killing motile sperm and/or fungi using the compounds and compositions.
REFERENCES:
patent: 2470108 (1949-05-01), Plati et al.
patent: 2470109 (1949-05-01), Plati et al.
patent: 2546652 (1951-03-01), Plati et al.
patent: 3408353 (1968-10-01), Jucker et al.
patent: 3462443 (1969-08-01), Paragamian
patent: 3497517 (1970-02-01), Jucker et al.
patent: 3574686 (1971-04-01), Jucker et al.
patent: 3627773 (1971-12-01), Ebnother et al.
patent: 3678057 (1972-07-01), Ebnother et al.
patent: 3678058 (1972-07-01), Ebnother et al.
patent: 3991066 (1976-11-01), Bastian et al.
patent: 5314917 (1994-05-01), Michaels et al.
patent: 5319084 (1994-06-01), Cook et al.
patent: 5952336 (1999-09-01), Cook et al.
patent: 6297278 (2001-10-01), Michaels et al.
Merck Manual, 16th ed., 1992, p. 1774.
C. E. Cook, et al., J. Med. Chem., vol. 38, pp. 753-763, “Structure-Acitivity Studies of 2,3,4,4a,5,9b-Hexahydroindeno[1,2-c]Pyridines as Antispermatogenic Agents for Male Contraception”, 1995.
G. De Meio, et al., Tetrahedron, vol. 49, No. 36, pp. 8129-8138, “Aryl Fluoride Syntheses Involving Reaction of Aryllead Triacetates With Boron Trifluoride-Diethyl Ether Complex”, 1993.
C. E. Cook, et al., Journal of Medicinal Chemistry, vol. 40, No. 14, pp. 2111-2112, “Exceptionally Potent Antispermatogenic Compounds From 8-Halogenation of (4aRS,5SR,9bRS)- Hexahydroindeno-[1,2-c]Pyridines”, Jul. 4, 1997.
S. A. Hild, et al., Biology of Reproduction, vol. 65, pp. 1771-1779, “Disruption of Spermatogenesis and Sertoli Cell Structure and Function by the Indenopyridine CDB-4022 in Rats”, 2001.
S. A. Hild, et al., Biology of Reproduction, vol. 65, pp. 165-172, “Lupron Depot Prevention of Antispermatogenic/Antifertility Activity of the Indenopyridine, CDB-4022, in the Rat”, 2001.
C. L.- T. Chang, et al., Biol. Pharm. Bull., vol. 25, No. 8, pp. 1097-1100, “Indenopyridine Hydrochloride Induced Testicular Spermatogenesis Failure With High Seminal Alkaline Phosphatase Levels in Male Dog”, 2002.
P. A. Fail, et al., Reproductive Toxicology, vol. 14, pp. 265-274, “28-Day Toxicology Test: Indenopyridine RTI 4587-056 in Male Sprague-Dawley Rats”, 2000.
J.M. Whitsett, et al. Effect of transitional photoperiods on testicular development and puberty in male deer mice(Peromyscus maniculatus), Journals of Reproduction & Fertility Ltd., vol. 72, pp. 277-286, 1984.
International Search Report, PCT/US04/00206.
Written Opinion, PCT/US04/00206.
Cook, et al., “Structure-Activity Studies of 2,3,4,4a,5,9b-Hexahydroindenol[1,2-c]pyridines as Antispermatogenic Agents for Male Contraception”, J. Med. Chem. 1995, 38, 753-763.
Mutation Research 1979,66(2), 113-127.
Cook Clarence Edgar
Navarro Hernan Andres
Sloan Carol Delta
Thomas Brian Frazier
Hui San-ming
Oblon & Spivak, McClelland, Maier & Neustadt P.C.
Research Triangle Institute
LandOfFree
Spermicidal and/or antifungal composition and methods of... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Spermicidal and/or antifungal composition and methods of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Spermicidal and/or antifungal composition and methods of... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4075892