Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2006-11-17
2009-06-09
Weber, Jon P (Department: 1656)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C424S278100, C514S013800, C930S010000
Reexamination Certificate
active
07544655
ABSTRACT:
Novel cell attachment peptides having sequences homologous to specific portions of the carboxy terminal sequence of fibrinogen chains are disclosed. The novel peptides, derived from proteins related to fibrinogen including a peptide adjacent to fibrinogen γ-chain C terminus denoted pre-Cγ possess cell attraction activities, and are useful in pharmaceutical compositions.
REFERENCES:
patent: 4455290 (1984-06-01), Olexa et al.
patent: 5372933 (1994-12-01), Zamarron et al.
patent: 5599790 (1997-02-01), Altieri et al.
patent: 5972654 (1999-10-01), Tang et al.
patent: 6037163 (2000-03-01), Tang et al.
patent: 6083902 (2000-07-01), Cederhom-Williams
patent: WO 99/61041 (1999-12-01), None
Moroi et al. (1998) Integrin-mediated platelet adhesion, Frontier Bisci., vol. 3, pp. 719-728.
Koonin et al. (2008, updated) Sequence-Evolution-Function, “Similarity, Homology, Divergence and Convergence”, pp. 1-7.
Duga et al. (200) Missense mutations in the human beta fibrinogen gene cause congenital afibrinogenemia by impairing fibrinogen secretion, Blood, vol. 95, No. 4, pp. 1336-1341.
Chung, D., et al., (1983) “Characterization Of Complementary Deoxyribonucleic Acid And Genomic Deoxyribonucleic Acid For The B Chain Of Human Fibrinogen”Biochemistry22:3244-3250.
Redman et al. (2001) “Fibrinogen Biosynthesis. Assembly, Intracellular Degradation, And Association With Lipid Synthesis And Secretion” Ann. N. Y.Acad. Sci. 936:480-495.
Watala, C. et al., (1996) “Microenvironmental Changes In Platelet Membranes Induced By The Interaction Of Fibrinogen-Derived Peptide Ligands With Platelet Integrins”Eur. J. Biochem.235:281-288.
Gorodetsky Raphael
Marx Gerard
Cooper & Dunham LLP
Hadasit Medical Research Services & Development Company Ltd
Liu Samuel W.
Weber Jon P
White John P.
LandOfFree
Haptotactic peptides does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Haptotactic peptides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Haptotactic peptides will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4073576