Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Chemical modification or the reaction product thereof – e.g.,...
Reexamination Certificate
2007-01-31
2009-08-04
Haq, Shafiqul (Department: 1641)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Chemical modification or the reaction product thereof, e.g.,...
C530S402000, C530S388900, C436S544000, C548S146000
Reexamination Certificate
active
07569678
ABSTRACT:
Activated haptens useful for generating immunogens to HIV protease inhibitors, immunogens useful for producing antibodies to HIV protease inhibitors, and antibodies and labeled conjugates useful in immunoassays for the HIV protease inhibitor saquinavir. The novel haptens feature an activated functionality at the central, non-terminal hydroxyl group. Also described are monoclonal antibodies specific for saquinavir having less than 10% cross-reactivity with lopinavir, nelfinavir, amprenavir, ritonavir, and indinavir, and a murine hybridoma producing said antibodies.
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Deras Ina
Huber Erasmus
Hui Raymond A.
Kern Peter
Metz Sigrun
Amick Marilyn L.
Haq Shafiqul
Roche Diagnostics Operations Inc.
Roche Diagnostics Operations Inc.
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