Drug – bio-affecting and body treating compositions – Plant material or plant extract of undetermined constitution...
Reexamination Certificate
2008-09-29
2009-08-25
Tate, Christopher R (Department: 1655)
Drug, bio-affecting and body treating compositions
Plant material or plant extract of undetermined constitution...
C424S779000, C424S777000, C424S774000
Reexamination Certificate
active
07579025
ABSTRACT:
This invention provides a process for extracting a pharmaceutically active fraction from the foliage (leaves and stems) and/or roots ofRauvolfia vomitoriaand the fruit ofCitrus aurantium. In one aspect, the process requires extracting from a boiled tea ofRauvolfia vomitoriafoliage and/or roots andCitrus aurantiumfruit an active fraction made by filtering the boiled tea and concentrating the supernatant. In one embodiment, the fraction is concentrated by freeze drying the supernatant. The fraction is useful to treat a disorder associated with abnormally elevated glucose levels in a subject by administering to the subject a therapeutically effective amount of the extract or a pharmaceutical composition containing the extract. Such conditions include, but are not limited to the diabetes Type II, abnormal steraroyl-CoA desaturase activity, hyperphagia, abnormal lipid mobilization, abnormal fatty acid profile from the eye of the subject, ulcers and a glucosuria.
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Written Opinion of the International Searching Authority. PCT/IB2005/004076. separate sheet. Sheet 2, Date of mailing Aug. 8, 2006.
Foley & Lardner LLP
Konski Antoinette F.
McCormick Melenie
Tate Christopher R
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