Monoclonal antibody to a human T cell antigen and methods of pre

Details Monoclonal antibody to a human T cell antigen and methods of pre Monoclonal antibody to a human T cell antigen and methods of pre

1980-01-08

1982-12-21

Fagelson, Anna P.

Drug, bio-affecting and body treating compositions

Lymphokine

260112R, 424101, 424177, 435 7, 435172, 435240, 435241, 436548, A61K 39395, C12N 500, C12N 502, C12N 1500, C12Q 100, G01N 3348, G01N 3368, G01N 3396

Patent

active

043649378

ABSTRACT:
Hybrid cell line for production of monoclonal antibody to an antigen found on essentially all normal human T cells and on approximately 95% of normal human thymocytes. The hybrid is formed by fusing splenocytes from immunized CAF.sub.1 mice with P3X63Ag8U1 myeloma cells. Diagnostic and therapeutic uses of the monoclonal antibody are also disclosed.

REFERENCES:
Kennett, SSIE Data Bank, Abstract of Grant, 5/77-4/79, Ab. No. 1 CA 189303.
Herzenberg et al., SSIE Data Bank, Abstract of Grant, 9/77-7/79, Ab. No. 1 CA 468120.
Williams, Cell, vol. 12, Nov. 1977, pp. 663-670, 672, 673.
Reinherz et al., (1) Proc. Nat. Acd. Sci. USA vol. 76, Aug. 1979, pp. 4061-4065.
Reinherz et al., (2) J. of Immunol. vol. 123, Sep. 1979, pp. 1312-1317.
Kung, Science, vol. 206, 19 Oct. 1979, pp. 347-349.
Melchers, (Ed. Lymph, Hybridomas, 2nd, Workshop on Functional Properties of Tumors of the Blymph, Spring-Verlag, Berlin/NY 1978, pp. IX-XVIII.
Yelton et al., Supra, pp. 1-7.
Trucco et al., Supra, pp. 66-69.
Levy et al., Supra, pp. 164-169.
Hammerling et al., Supra, pp. 100-106.
Iverson et al., Supra, pp. 192-194.
Simpson et al., Supra, pp. 195-202.
Ruddle, Supra, pp. 203-211.
Taniguchi et al., Supra, pp. 212-216.
Osborne et al., Supra, pp. 217-220.
Saravia et al., Supra, pp. 224-231.
Barnstable et al., Cell, vol. 14, May 1978, pp. 9-20.
Fox, C & E News, Jan. 1, 1979, pp. 15-17.
White et al., J. Exptl. Med. vol. 148, 1 Sep. 1978, pp. 664-673.
Herzenberg et al., from Weir (ED) Handbook of Exptl. Immunol, Blackwell, London 3rd Ed., 1978, pp. 25.1-25.7.
Cosimi et al., Surgery, vol. 40, 1976, pp. 155-163.
Lampson et al., J. Supramolecular Structure, vol. 6, 1977, pp. 441-448.
Tracco, Nature, vol. 273, 22 Jun. 1978, pp. 666-668.

Affiliated with

Also associated with

Rating

Monoclonal antibody to a human T cell antigen and methods of pre does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Monoclonal antibody to a human T cell antigen and methods of pre, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Monoclonal antibody to a human T cell antigen and methods of pre will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-405980