Diagnosis and treatment of disorders of iron metabolism

Details Diagnosis and treatment of disorders of iron metabolism Diagnosis and treatment of disorders of iron metabolism

2002-09-12

2009-10-13

Allen, Marianne P (Department: 1647)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C435S007100, C435S007920, C435S004000, C436S008000, C436S518000, C436S501000, C530S397000

Reexamination Certificate

active

07601684

ABSTRACT:
The invention concerns a method for detecting disorders of iron metabolism and in particular the differential diagnosis of disorders of iron metabolism by means of three independent parameters. The differential diagnosis can be used to classify disorders of iron metabolism and to recommend the required treatment and to monitor the progress and response to treatment.

REFERENCES:
Little et al. Hemochromatosis:Diagnosis and Management. American Family Physician, vol. 53/8, pp. 2623-2628 (1996).
Feelders et al. Regulation of iron metabolism in the acute-phase response:interferon gamma and tumor necrosis factor alpha induce hypoferraemia, ferritin production and a decrease in circulating transferrin receptors in cancer patients. European Journal of Clinical Investigation vol. 28:520-527 (1998).
Suominen et al. Single values of serum transferrin receptor and transferrin receptor ferritin index can be used to detect true and functional iron deficiency in rheumatoid arthritis patients with anemia. Arthritis and Rheumatism vol. 43/5:1016-1020 (May 2000).
Lehmann, P. et al. Clinical Chemistry and Laboratory Medicine, 39(Special Supplement), pp. S338, Abstract PO-T011, May 2001.
Lehmann, P. et al. Onkologie, 23(Sonderheft 7), p. 193, A bstract 0742, Oct. 2000.
Thomas et al., Clinical Chemistry, 48(7):1066-1076, 2002.
Lehmann et al., Clinical Chemistry, 48(6, supplement), pp. A33-A34, Abstract A-103, 2002.
Looker et al. Increased serum transferrin saturation is associated with lower serum transferrin receptor concentration. Clinical Chemistry, 45:12, pp. 2191-2199 (1999).
Fishbane et al. Reticulocyte hemoglobin content in the evaluation of iron status of hemodialysis patients. Kidney International, vol. 52, pp. 217-222 (1997).
Remacha et al. The role of serum transferrin receptor in the diagnosis of iron deficiency. Haematologica 83:963-966 (1998).
Bovy, et al.,Factors determining the percentage of hypochromic red blood cells in hemodialysis patients, Kidney International, vol. 56, pp. 1113-1119 (1999).
Tessitore, et al.,The role of iron status markers in predicting response to intravenous iron in haemodialysis patients on maintenance erythropoietin, Nephrology Dialysis Transplantation, vol. 16, pp. 1416-1423 (2001).
Thomas, et al.,Biochemical Markers and Hematologic Indices in the Diagnosis of Functional Iron Deficiency, Clinical Chemistry, vol. 48, pp. 1066-1076 (2002).
Hasegawa, Midori, et al., Evaluation of reticulocyte hemoglobin content, percentage of hypochromic red blood cells, and ratio of serum transferring receptor level/serum iron level as markers of iron-deficiency erythropoiesis in patients undergoing hemodialysis, NLM Database accession No. NLM12216478 XP002247472 abstract of Nippon Jinzo Gakkai Shi, Japan 2002, vol. 44. No. 5, pp. 453-463, ISSN: 0385-2385.
Suominen, Pauli, et al.,Single Values of Serum Transferrin Receptor and Transferrin Receptor Ferritin Index Can be Used to Detect True and Functional Iron Deficiency in Rheumatoid Arthritis Patients with Anemmia, Arthritis & Rheumatism, 43:1016-1020 (2000).
Feelders, R.A., et al.,Regulation of iron metabolism in the acute-phase response: interferon γ and tumour necrosis factor α induce hypoferraemia, ferritin production and a decrease in circulating transferrin receptors in cancer patients, European Journal of Clinical Investigation, 28:520-527 (1998).
Looker, A., et al.,Increased Serum Transferrin Saturation Is Associated with Lower Serum Transferrin Receptor Concentration, Clinical Chemistry, 45:2191-2199 (1999).
Beguin, Y., et al.,Acute functional iron deficiency in obese subjects during a very-low energy all-protein diet, American Journal of Clinical Nutrition, 66:75-79 (1997).
Fishbane, S., et al.,Reticulocyte hemoglobin content in the evaluation of iron status of hemodialysis patients, Kidney International, 52:217-222 (1997).

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