Gene reporter assay, kit, and cells for determining the...

Details Gene reporter assay, kit, and cells for determining the... Gene reporter assay, kit, and cells for determining the...

2003-10-03

2008-12-30

Qian, Celine X (Department: 1636)

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

C435S455000

Reexamination Certificate

active

07470536

ABSTRACT:
The present invention relates to a commercializable cell and to a gene reporter assay method and a kit which use this cell to determine the presence and/or the level of a molecule that activates signal transduction activity of a cell surface protein. This cell is treated in such a manner that it will have a sufficiently long shelf life for its intended purpose, whereupon at the end of its useful shelf life or at the end of its use, i.e., in an assay, the cell undergoes cellular death.

REFERENCES:
patent: 5401629 (1995-03-01), Harpold et al.
patent: 5436128 (1995-07-01), Harpold et al.
patent: 5707803 (1998-01-01), Lamb et al.
patent: 7045281 (2006-05-01), Livelli et al.
Button et al. Aequorin-expressing mammalian cell lines used to report Ca2+ mobilization. Cell Calcium (Oct. 1993) vol. 14(9), pp. 663-671.
Ahern H. Biochemical, reagents kits offer scientists good return on investment. The Scientist (1995) vol. 9, issue 15, pp. 20-27.
Ausubel et al (Current Protocols in Molecular Biology, vol. 4, pp. A.3F.5-10).
Lallemand et al., Constitutive expression of specific interferon isotypes in peripheral blood leukocytes from normal individuals and in promonocytic U937 cells,Journal of Leukocyte Biology, 60:137-146 (1996).
Canosi et al., A highly precise reporter gene bioassay for type I interferon,Journal of Immunological Methods, 199:69-76 (1996).
Lewis, A sensitive biological assay for interferons,Journal of Immunological Methods, 185:9-17 (1995).
Files et al., A novel sensitive and selective bioassay for human type I interferons,Journal of Interferon and Cytokine Research, 18:1019-1024 (1998).
Hammerling et al., The β-Gal interferon assay: A new, precise, and sensitive method,Journal of Interferon and Cytokine Research, 18:451-460 (1998).

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